ArticleMethods in molecular biology (Clifton, N.J.)2015
Determining the Effects of Membrane-Interacting Peptides on Membrane Integrity.
Article in Methods in molecular biology (Clifton, N.J.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- A unified model of transient poration induced by antimicrobial peptides.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Insights into Membrane Damage byBiomolecules · 2025Article
- Characterization of a New Immunosuppressive and Antimicrobial Peptide, DRS-DA2, Isolated from the Mexican Frog,International journal of inflammation · 2024Article
- Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents.Frontiers in pharmacology · 2024Article
- Article
- Effects of cholesterol on the mechanism of fengycin, a biofungicide.Biophysical journal · 2022Article
- A Limitation of Using Dithionite Quenching to Determine the Topology of Membrane-inserted Proteins.The Journal of membrane biology · 2022Article
- The effect of membrane thickness on the membrane permeabilizing activity of the cyclic lipopeptide tolaasin II.Frontiers in molecular biosciences · 2022Article
- Membrane-selective nanoscale pores in liposomes by a synthetically evolved peptide: implications for triggered release.Nanoscale · 2021Article
- Understanding the Antibacterial Resistance: Computational Explorations in Bacterial Membranes.ACS omega · 2021Review
- Functional and Structural Variation among Sticholysins, Pore-Forming Proteins from the Sea AnemoneInternational journal of molecular sciences · 2020Review
- Membrane activity of two short Trp-rich amphipathic peptides.Biochimica et biophysica acta. Biomembranes · 2020Article
- Mechanistic Landscape of Membrane-Permeabilizing Peptides.Chemical reviews · 2019Review
- The Mechanism of Membrane Permeabilization by Peptides: Still an Enigma.Australian journal of chemistry · 2019Article
- Identification of Peptides in Flowers ofMolecules (Basel, Switzerland) · 2018Article
- Spontaneous Membrane Translocating Peptides: The Role of Leucine-Arginine Consensus Motifs.Biophysical journal · 2017Article
- Ebola Virus Delta Peptide Is a Viroporin.Journal of virology · 2017Article
- Conformational Fine-Tuning of Pore-Forming Peptide Potency and Selectivity.Journal of the American Chemical Society · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
In the study of cell-penetrating and membrane-translocating peptides, a fundamental question occurs as to the contribution arising from fundamental peptide-membrane interactions, relative to the contribution arising from the biology and energy of the cell, mostly occurring in the form of endocytosis and subsequent events. A commonly used approach to begin addressing these mechanistic questions is to measure the degree to which peptides can interact with, and physically disrupt, the integrity of synthetic lipid bilayers. Here, we describe a set of experimental methods that can be used to measure the potency, kinetics, transience, and the effective size of peptide-induced membrane disruption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.