Evidence map›Paper›PMID 26201843›Full record

ReviewCurrent opinion in cell biology2015

Running with neighbors: coordinating cell migration and cell-cell adhesion.

Caitlin Collins, W James Nelson

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 138 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caitlin CollinsDepartment of Biology, Stanford University, Stanford, CA 94305, USA.
W James NelsonDepartment of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: wjnelson@stanford.edu.
Stanford University · US

Funding

TRAINING & OUTREACH COREP50GM107615 · NIGMS · STANFORD UNIVERSITY · PI FERRELL, JAMES E. · 2013 to 2017
$10.9M
Topogenesis of NA/K-ATPASE in Polarized Epithelial CellsR37GM035527 · NIGMS · STANFORD UNIVERSITY · PI NELSON, W. JAMES · 2003 to 2012
$7.4M
TUMOR BIOLOGYT32CA009151 · NCI · STANFORD UNIVERSITY · PI CLEARY, MICHAEL L · 1985 to 2014
$5.5M
Topogenesis of Na/K-ATPase in Polarized MDCK Epithelial CellsR01GM035527 · NIGMS · STANFORD UNIVERSITY · PI NELSON, W. JAMES · 1986 to 2015
$3.3M
Cell-Cell Junctions and Epithelial HomeostasisR35GM118064 · NIGMS · STANFORD UNIVERSITY · PI STEARNS, TIM · 2016 to 2018
$2.6M
NCI NIH HHS T32 CA009151NCI NIH HHS T32 CA09151NIGMS NIH HHS GM 35527NIGMS NIH HHS P50 GM107615NIGMS NIH HHS R01 GM035527NIGMS NIH HHS R35 GM118064NIGMS NIH HHS R37 GM035527
6 · The paper itself

Abstract

Coordinated movement of large groups of cells is required for many biological processes, such as gastrulation and wound healing. During collective cell migration, cell-cell and cell-extracellular matrix (ECM) adhesions must be integrated so that cells maintain strong interactions with neighboring cells and the underlying substratum. Initiation and maintenance of cadherin adhesions at cell-cell junctions and integrin-based cell-ECM adhesions require integration of mechanical cues, dynamic regulation of the actin cytoskeleton, and input from specific signaling cascades, including Rho family GTPases. Here, we summarize recent advances made in understanding the interplay between these pathways at cadherin-based and integrin-based adhesions during collective cell migration and highlight outstanding questions that remain in the field.

Indexed as

Cell MovementBiochemical PhenomenaCell AdhesionCell-Matrix JunctionsExtracellular MatrixSignal Transduction

Identifiers

PMID26201843
PMCPMC4639402
OpenAlexW933385811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.