Evidence map›Paper›PMID 26201816›Full record

ArticleThe American journal of clinical nutrition2015

Best (but oft-forgotten) practices: checking assumptions concerning regression residuals.

Lawrence E Barker, Kate M Shaw

Abstract read
In one paragraph

Article in The American journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  3. Optimizing CT-Based Models for Predicting Whole-Body Fat in Rabbits.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Nature's Master of Ceremony: TheNpj biological timing and sleep · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Data Distribution: Normal or Abnormal?Journal of Korean medical science · 2024
    Review
  14. Article
  15. The Relationship between the Frontal QRS-T Angle on ECG and Physical Activity Level in Young Adults.International journal of environmental research and public health · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lawrence E BarkerCenters for Disease Control and Prevention, Chamblee, GA lsb8@cdc.gov.
Kate M ShawCenters for Disease Control and Prevention, Chamblee, GA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The residuals of a least squares regression model are defined as the observations minus the modeled values. For least squares regression to produce valid CIs and P values, the residuals must be independent, be normally distributed, and have a constant variance. If these assumptions are not satisfied, estimates can be biased and power can be reduced. However, there are ways to assess these assumptions and steps one can take if the assumptions are violated. Here, we discuss both assessment and appropriate responses to violation of assumptions.

Indexed as

Least-Squares AnalysisLinear ModelsModels, TheoreticalAnalysis of VarianceStatistics as Topicassumptionsnormalityregressionresidualsstatisticsvariance

Identifiers

PMID26201816
PMCPMC4558311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.