Evidence map›Paper›PMID 26201721›Full record

ArticleBMJ open2015

Farm environment during infancy and lung function at the age of 31: a prospective birth cohort study in Finland.

Jussi Lampi, Heikki Koskela, Anna-Liisa Hartikainen, Adaikalavan Ramasamy, Alexessander Couto Alves, Marjo-Riitta Järvelin, Juha Pekkanen

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In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jussi LampiDepartment of Health Protection, National Institute for Health and Welfare, Kuopio, Finland Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Heikki KoskelaCenter for Medicine and Clinical Research, Division of Pulmonary Medicine, Kuopio University Hospital, Kuopio, Finland.
Anna-Liisa HartikainenDepartment of Obstetrics and Gynecology and MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Adaikalavan RamasamyRespiratory Epidemiology and Public Health, Imperial College London, London, UK Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK Department of Medical and Molecular Genetics, King's College London, London, UK.
Alexessander Couto AlvesDepartment of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Marjo-Riitta JärvelinDepartment of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK Institute of Health Sciences, University of Oulu, Oulu, Finland Biocenter Oulu, University of Oulu, Oulu, Finland Unit of Primary Care, Oulu University Hospital, Oulu, Finland Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland.
Juha PekkanenDepartment of Health Protection, National Institute for Health and Welfare, Kuopio, Finland Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.

Funding

Department of Health
6 · The paper itself

Abstract

objectivesFarming as an occupation is considered a risk factor for asthma and reduced lung function. By contrast, living on a farm during infancy has been reported to be associated with lower risk of asthma in adulthood. However, little is known about the association between farming environment during infancy and lung function in adulthood. We aimed to study the prospective longitudinal association between farming environment during infancy and lung function in adulthood.

designA prospective birth cohort study.

settingNorthern Finland.

participants5666 participants born in 1966 were followed up at the age of 31 years. PRIMARY OUTCOME MEASURES: Spirometry at the age of 31 years.

resultsTo be born into a farmer's family was associated with higher forced expiratory volume in 1 s (FEV1) (36 mL; 95% CI 6 to 67 mL) and forced vital capacity (FVC) (40 mL; 95% CI 5 to 75 mL) at the age of 31 years. Contact with farm animals during infancy was associated with higher FEV1. No associations were seen with FEV1/FVC (FEV1/FVC ratio). Having dogs in childhood revealed similar associations. There was a suggestive dose-dependent association with the number of animal species during childhood and higher FEV1 and FVC at adulthood, especially among women.

conclusionsFarming environment in early life may have a positive impact on lung function in adulthood.

Indexed as

AgricultureAdultAnimalsAnimals, DomesticAsthmaCatsCohort StudiesDogsEnvironmental ExposureFemaleFinlandForced Expiratory VolumeHumansLungMalePetsEPIDEMIOLOGYOCCUPATIONAL & INDUSTRIAL MEDICINERESPIRATORY MEDICINE (see Thoracic Medicine)

Identifiers

PMID26201721
PMCPMC4513452

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.