Evidence map›Paper›PMID 26201441›Full record

ReviewClinical and experimental immunology2016

RNA binding proteins as regulators of immune cell biology.

R Newman, J McHugh, M Turner

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical and experimental immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 57 citations in OpenAlex.

  1. The effects of leukocyteBMC veterinary research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

R NewmanBabraham Institute, Cambridge, UK.
J McHughBabraham Institute, Cambridge, UK.
M TurnerBabraham Institute, Cambridge, UK.
Babraham Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/J00152X/1Biotechnology and Biological Sciences Research Council BBS/E/B/0000M740Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407Medical Research Council G0601618
6 · The paper itself

Abstract

Sequence-specific RNA binding proteins (RBP) are important regulators of the immune response. RBP modulate gene expression by regulating splicing, polyadenylation, localization, translation and decay of target mRNAs. Increasing evidence suggests that RBP play critical roles in the development, activation and function of lymphocyte populations in the immune system. This review will discuss the post-transcriptional regulation of gene expression by RBP during lymphocyte development, with particular focus on the Tristetraprolin family of RBP.

Indexed as

AnimalsCell DifferentiationGene Expression RegulationHumansLymphocyte ActivationLymphocytesRNA-Binding ProteinsRNA, MessengerRNA Processing, Post-TranscriptionalTristetraprolinRNA-Binding ProteinsRNA, MessengerTristetraprolincell activationgene regulationinflammation

Identifiers

PMID26201441
PMCPMC4687516
OpenAlexW1848707611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.