Evidence map›Paper›PMID 26200979›Full record

ArticleThe New England journal of medicine2015

Long-Term Outcomes of Abdominal Aortic Aneurysm in the Medicare Population.

Marc L Schermerhorn, Dominique B Buck, A James O'Malley, Thomas Curran, John C McCallum, Jeremy Darling, Bruce E Landon

Registry-linked trialOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04532450 (Outcomes of Fenestrated and Branched Stent Grafts to Treat Secondary Type 1 Endoleak After Endovascular Aneurysm Repair), which is not on this map. Cited by 153 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed, 5 pooled it
33.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04532450 completednot on this map

Outcomes of Fenestrated and Branched Stent Grafts to Treat Secondary Type 1 Endoleak After Endovascular Aneurysm Repair : A Prospective Multicentre Study

TypeobservationalSponsorUniversity Paul Sabatier of ToulouseRan2010 to 2019Enrolled85ConditionsAbdominal Aortic AneurysmArmsBranched / fenestrated aortic stent graft
3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 5 syntheses or guidelines pooled it, 494 citations in OpenAlex.

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  15. Laser fenestration and shape memory polymer embolization of type II endoleaks.Journal of vascular surgery cases and innovative techniques · 2026
    Article
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93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Marc L SchermerhornFrom the Departments of Surgery (M.L.S., D.B.B., T.C., J.C.M, J.D.) and Medicine (B.E.L.), Beth Israel Deaconess Medical Center, and the Department of Health Care Policy, Harvard Medical School (B.E.L.) - both in Boston; and the Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH (A.J.O.).
Dominique B Buck
A James O'Malley
Thomas Curran
John C McCallum
Jeremy Darling
Bruce E Landon
Hadassah Medical Center · ILDartmouth Institute for Health Policy and Clinical Practice · US

Funding

HARVARD-LONGWOOD RESEARCH TRAINING IN VASCULAR SURGERYT32HL007734 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FERRAN, CHRISTIANE, LOGERFO, FRANK W · 1993 to 2023
$10.5M
Long Term Outcomes of Open Versus Endovascular AAA RepairR01HL105453 · NHLBI · HARVARD MEDICAL SCHOOL · PI LANDON, BRUCE E., SCHERMERHORN, MARC · 2011 to 2013
$2.0M
Accounting for confounding bias and heterogeneity in comparative effectivenessRC4MH092717 · NIMH · HARVARD MEDICAL SCHOOL · PI O'MALLEY, ALISTAIR JAMES · 2010 to 2010
$1.5M
NHLBI NIH HHS 5R01HL105453-03NHLBI NIH HHS R01 HL105453NHLBI NIH HHS T32 HL007734NIMH NIH HHS 1RC4MH092717-01NIMH NIH HHS RC4 MH092717
6 · The paper itself

Abstract

backgroundRandomized trials and observational studies have shown that perioperative morbidity and mortality are lower with endovascular repair of abdominal aortic aneurysm than with open repair, but the survival benefit is not sustained. In addition, concerns have been raised about the long-term risk of aneurysm rupture or the need for reintervention after endovascular repair.

methodsWe assessed perioperative and long-term survival, reinterventions, and complications after endovascular repair as compared with open repair of abdominal aortic aneurysm in propensity-score-matched cohorts of Medicare beneficiaries who underwent repair during the period from 2001 through 2008 and were followed through 2009.

resultsWe identified 39,966 matched pairs of patients who had undergone either open repair or endovascular repair. The overall perioperative mortality was 1.6% with endovascular repair versus 5.2% with open repair (P<0.001). From 2001 through 2008, perioperative mortality decreased by 0.8 percentage points among patients who underwent endovascular repair (P=0.001) and by 0.6 percentage points among patients who underwent open repair (P=0.01). The rate of conversion from endovascular to open repair decreased from 2.2% in 2001 to 0.3% in 2008 (P<0.001). The rate of survival was significantly higher after endovascular repair than after open repair through the first 3 years of follow-up, after which time the rates of survival were similar. Through 8 years of follow-up, interventions related to the management of the aneurysm or its complications were more common after endovascular repair, whereas interventions for complications related to laparotomy were more common after open repair. Aneurysm rupture occurred in 5.4% of patients after endovascular repair versus 1.4% of patients after open repair through 8 years of follow-up (P<0.001). The rate of total reinterventions at 2 years after endovascular repair decreased over time (from 10.4% among patients who underwent procedures in 2001 to 9.1% among patients who underwent procedures in 2007).

conclusionsEndovascular repair, as compared with open repair, of abdominal aortic aneurysm was associated with a substantial early survival advantage that gradually decreased over time. The rate of late rupture was significantly higher after endovascular repair than after open repair. The outcomes of endovascular repair have been improving over time. (Funded by the National Institutes of Health.).

Indexed as

Endovascular ProceduresAgedAged, 80 and overAortic Aneurysm, AbdominalAortic RuptureFemaleFollow-Up StudiesHumansLaparotomyMaleMedicarePostoperative ComplicationsPropensity ScoreReoperationSurvival RateTreatment Outcome

Identifiers

PMID26200979
PMCPMC4532303
OpenAlexW2255050058

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.