ArticleArquivos brasileiros de cardiologia2015
Experience of ECMO in primary graft dysfunction after orthotopic heart transplantation.
Article in Arquivos brasileiros de cardiologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Understanding the "extracorporeal membrane oxygenation gap" in veno-arterial configuration for adult patients: Timing and causes of death.Artificial organs · 2021Pooled it
- Risk Estimation of Severe Primary Graft Dysfunction in Heart Transplant Recipients Using a Smartphone.Reviews in cardiovascular medicine · 2025Article
- Extracorporeal Membrane Oxygenation in Postcardiotomy Cardiogenic Shock.Methodist DeBakey cardiovascular journal · 2023Review
- Predictors of mortality following extracorporeal membrane oxygenation support in an unselected, critically ill patient population.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2021Article
- Financial implications of using extracorporeal membrane oxygenation following heart transplantation.Interactive cardiovascular and thoracic surgery · 2021Article
- A case series: the outcomes, support duration, and graft function recovery after VA-ECMO use in primary graft dysfunction after heart transplantation.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2020Article
- Structured review of post-cardiotomy extracorporeal membrane oxygenation: part 1-Adult patients.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2019Review
- Review
- Extracorporeal membrane oxygenation use in the first 24 hours following pediatric heart transplantation: Incidence, risk factors, and outcomes.Pediatric transplantation · 2019Article
- There is one more thing to be done: ECMO!Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia CardiovascularArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary graft dysfunction is the main cause of early mortality after heart transplantation. Mechanical circulatory support has been used to treat this syndrome.
objectiveDescribe the experience with extracorporeal membrane oxygenation to treat post-transplant primary cardiac graft dysfunction.
methodsBetween January 2007 and December 2013, a total of 71 orthotopic heart transplantations were performed in patients with advanced heart failure. Eleven (15.5%) of these patients who presented primary graft dysfunction constituted the population of this study. Primary graft dysfunction manifested in our population as failure to wean from cardiopulmonary bypass in six (54.5%) patients, severe hemodynamic instability in the immediate postoperative period with severe cardiac dysfunction in three (27.3%), and cardiac arrest (18.2%). The average ischemia time was 151 ± 82 minutes. Once the diagnosis of primary graft dysfunction was established, we installed a mechanical circulatory support to stabilize the severe hemodynamic condition of the patients and followed their progression longitudinally.
resultsThe average duration of extracorporeal membrane oxygenation support was 76 ± 47.4 hours (range 32 to 144 hours). Weaning with cardiac recovery was successful in nine (81.8%) patients. However, two patients who presented cardiac recovery did not survive to hospital discharge.
conclusionMechanical circulatory support with central extracorporeal membrane oxygenation promoted cardiac recovery within a few days in most patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.