SynthesisPsychological medicine2015
Religious and spiritual interventions in mental health care: a systematic review and meta-analysis of randomized controlled clinical trials.
Synthesis in Psychological medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 11 syntheses or guidelines pooled it, 376 citations in OpenAlex.
- Spirituality and Medicine in the USA, Europe, and the UK: A Systematic Review and Meta-analysis of Integrative Approaches to Patient Satisfaction, Quality of Life, and Health Outcomes.Journal of religion and health · 2026Pooled it
- Effectiveness, barriers, and facilitators of interventions delivered by traditional healers for the treatment of common mental disorders: A systematic review.Transcultural psychiatry · 2024Pooled it
- Factors Influencing the Quality of Life (QOL) of Advanced Cancer Patients in Home-based Palliative Care (HBPC): A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2024Pooled it
- The effects of nurse-led spiritual care on psychological well-being in the healthcare services of patients with cardiovascular diseases in Iran: a systematic review.BMC cardiovascular disorders · 2024Pooled it
- Religiosity and spirituality in the prevention and management of depression and anxiety in young people: a systematic review and meta-analysis.BMC psychiatry · 2023Pooled it
- The role of religiosity and spirituality in interpersonal violence: a systematic review and meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2023Pooled it
- The Influence of Religiosity and Spirituality on Health in Canada: A Systematic Literature Review.Journal of religion and health · 2022Pooled it
- Association between spirituality/religiousness and quality of life among healthy adults: a systematic review.Health and quality of life outcomes · 2021Pooled it
- Spirituality-Integrated Interventions for Caregivers of Patients with Terminal Illness: A Systematic Review of Quantitative Outcomes.Journal of religion and health · 2021Pooled it
- Quality of life of cancer patients at palliative care units in developing countries: systematic review of the published literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Pooled it
- Pooled it
- Trial
- Effect of nurse-led intervention programs based on spiritual care on the resilience and death anxiety in parents of children and adolescents with cancer, a randomized clinical trial.BMC psychology · 2025Trial
- Trial
- The Effect of Religious-Spiritual Psychotherapy on Illness Perception and Inner Strength among Patients with Breast Cancer in Iran.Journal of religion and health · 2022Trial
- The Effect of Religion Intervention on Life Satisfaction and Depression in Elderly with Heart Failure.Journal of religion and health · 2019Trial
- Integrating Spiritual Care Teaching Within the Australian Medical Curriculum.The clinical teacher · 2026Article
- The Impact of Spirituality, Religiosity, and Quality of Life on the Survival of Patients with Head-and-Neck Squamous Cell Carcinoma in Brazil: A Cohort Study.Journal of religion and health · 2026Article
- Language-dependent expression of anxiety and depression symptoms in Japanese-English bilinguals.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- What is 'Spiritual Health'? A Survey of Social Prescribers in the United Kingdom.Journal of religion and health · 2026Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the extensive literature assessing associations between religiosity/spirituality and health, few studies have investigated the clinical applicability of this evidence. The purpose of this paper was to assess the impact of religious/spiritual interventions (RSI) through randomized clinical trials (RCTs).
methodA systematic review was performed in the following databases: PubMed, Scopus, Web of Science, PsycINFO, Cochrane Collaboration, Embase and SciELO. Through the use of a Boolean expression, articles were included if they: (i) investigated mental health outcomes; (ii) had a design consistent with RCTs. We excluded protocols involving intercessory prayer or distance healing. The study was conducted in two phases by reading: (1) title and abstracts; (2) full papers and assessing their methodological quality. Then, a meta-analysis was carried out.
resultsThrough this method, 4751 papers were obtained, of which 23 remained included. The meta-analysis showed significant effects of RSI on anxiety general symptoms (p < 0.001) and in subgroups: meditation (p < 0.001); psychotherapy (p = 0.02); 1 month of follow-up (p < 0.001); and comparison groups with interventions (p < 0.001). Two significant differences were found in depressive symptoms: between 1 and 6 months and comparison groups with interventions (p = 0.05). In general, studies have shown that RSI decreased stress, alcoholism and depression.
conclusionsRCTs on RSI showed additional benefits including reduction of clinical symptoms (mainly anxiety). The diversity of protocols and outcomes associated with a lack of standardization of interventions point to the need for further studies evaluating the use of religiosity/spirituality as a complementary treatment in health care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.