ArticleInvestigative ophthalmology & visual science2015
Visual Prognosis of Eyes Recovering From Macular Hole Surgery Through Automated Quantitative Analysis of Spectral-Domain Optical Coherence Tomography (SD-OCT) Scans.
Article in Investigative ophthalmology & visual science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- VALIDATION OF A DEEP LEARNING-BASED ALGORITHM FOR SEGMENTATION OF THE ELLIPSOID ZONE ON OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AN USH2A-RELATED RETINAL DEGENERATION CLINICAL TRIAL.Retina (Philadelphia, Pa.) · 2022Trial
- Longitudinal Assessment of Ellipsoid Zone Integrity, Subretinal Hyperreflective Material, and Subretinal Pigment Epithelium Disease in Neovascular Age-Related Macular Degeneration.Ophthalmology. Retina · 2021Trial
- Beyond Performance Metrics: Automatic Deep Learning Retinal OCT Analysis Reproduces Clinical Trial Outcome.Ophthalmology · 2020Trial
- Inverted internal limiting membrane flap technique versus internal limiting membrane removal in large macular hole with different hole edge configurations: a comparative study.Frontiers in medicine · 2026Article
- Prediction of visual recovery after idiopathic macular hole surgery: a triad of tractional mechanics, subfoveal anatomy, and preoperative function.International journal of ophthalmology · 2026Article
- Dynamic Structural Recovery Parameters Enhance Prediction of Visual Outcomes After Macular Hole Surgery.Translational vision science & technology · 2025Article
- Frequently assessed and used prognostic factors for outcome after macular hole surgery: which is better?BMC ophthalmology · 2021Article
- Imaging and artificial intelligence for progression of age-related macular degeneration.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Ellipsoid Zone and External Limiting Membrane-Related Parameters on Spectral Domain-Optical Coherence Tomography and Their Relationships With Visual Prognosis After Successful Macular Hole Surgery.Frontiers in medicine · 2021Article
- Thickness of the Macula, Retinal Nerve Fiber Layer, and Ganglion Cell-inner Plexiform Layer in the Macular Hole: The Repeatability Study of Spectral-domain Optical Coherence Tomography.Korean journal of ophthalmology : KJO · 2018Article
- Preoperative and postoperative features of macular holes on en face imaging and optical coherence tomography angiography.American journal of ophthalmology case reports · 2017Article
- Automated intraretinal segmentation of SD-OCT images in normal and age-related macular degeneration eyes.Biomedical optics express · 2017Article
- Clinical and histological evaluation of large macular hole surgery using the inverted internal limiting membrane flap technique.Clinical ophthalmology (Auckland, N.Z.) · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo determine the value of topographic spectral-domain optical coherence tomography (SD-OCT) imaging features assessed after macular hole repair surgery in predicting visual acuity (VA) outcomes.
methodsAn automated algorithm was developed to topographically outline and quantify area, extent, and location of defects in the ellipsoid zone (EZ) band and inner retina layers in SD-OCT scans. We analyzed the correlation of these values with VA in longitudinal observations from 35 patients who underwent successful macular hole surgery, in their first observation after surgery (within 2 months), and in a single observation within 6 to 12 months after surgery. Image features assessed at the first visit after surgery were also investigated as possible predictors of future VA improvement.
resultsSignificant correlation with longitudinal VA was found for the extent, circularity, and ratio of defects in EZ band at the fovea and parafoveal regions. The ratio of defects in EZ band at the fovea, temporal-inner, and inferior-inner macula regions showed significant strong correlation with VA within 6 to 12 months post surgery. Patients with worse vision outcome at such time also had a significantly higher rate of inner retinal defects in the superior-outer region in their first postsurgery observation.
conclusionsA lowering extent of EZ band defects in the foveal and parafoveal regions is a good indicator of postsurgery VA recovery. Attention should also be given to postsurgical alterations in the inner retina, as patients with more extensive atrophic changes appear to have slower or worse VA recovery despite closure of the macular hole.
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