ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2015
Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis.
Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 67 citations in OpenAlex.
- Dysregulation of AR and ERα caused ovarian alterations in gerbils prenatally exposed to 17α-ethinylestradiol and pequi oil.Histochemistry and cell biology · 2025Article
- On the Path to a Sustainable Diet: Native Brazilian Fruits of the Caryocar spp. (Pequi and Piquiá) and Potential Health Benefits in Chronic Kidney Disease.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Review
- Pequi Pulp (Polymers · 2025Article
- Combinatory Effect of Pequi Oil (Pharmaceutics · 2024Article
- Antiproliferative effect of indeno[1,2-d]thiazolo[3,2-a]pyrimidine analogues on IL-6 mediated STAT3 and role of the apoptotic pathway in albino Wistar rats of ethyl carbamate-induced lung carcinoma: In-silico, In-vitro, and In-vivo study.Cancer cell international · 2024Article
- Pequi Oil (Animals : an open access journal from MDPI · 2023Article
- Potential Challenges of the Extraction of Carotenoids and Fatty Acids from Pequi (Foods (Basel, Switzerland) · 2023Review
- Phenolic profile of jujube fruit subjected to gut microbiota fermentation and its antioxidant potential against ethyl carbamate-induced oxidative damage.Journal of Zhejiang University. Science. B · 2021Article
- Pequi (Pharmaceutics · 2020Article
- Caryocar brasiliense oil improves cardiac function by increasing Serca2a/PLB ratio despite no significant changes in cardiovascular risk factors in rats.Lipids in health and disease · 2017Article
- Hepatitis B virus X protein (HBx)-induced abnormalities of nucleic acid metabolism revealed by (1)H-NMR-based metabonomics.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The antioxidant effects of Caryocar brasiliense Camb, commonly known as the pequi fruit, have not been evaluated to determine their protective effects against oxidative damage in lung carcinogenesis. In the present study, we evaluated the role of pequi fruit against urethane-induced DNA damage and oxidative stress in forty 8-12 week old male BALB/C mice. An in vivo comet assay was performed to assess DNA damage in lung tissues and changes in lipid peroxidation and redox cycle antioxidants were monitored for oxidative stress. Prior supplementation with pequi oil or its extract (15 µL, 60 days) significantly reduced urethane-induced oxidative stress. A protective effect against DNA damage was associated with the modulation of lipid peroxidation and low protein and gene expression of nitric oxide synthase. These findings suggest that the intake of pequi fruit might protect against in vivo genotoxicity and oxidative stress.
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Registered trials
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