Evidence map›Paper›PMID 26200119›Full record

ArticleEnvironmental science. Nano2015

An integrated methodology for the assessment of environmental health implications during thermal decomposition of nano-enabled products.

Georgios A Sotiriou, Dilpreet Singh, Fang Zhang, Wendel Wohlleben, Marie-Cecile G Chalbot, Ilias G Kavouras, Philip Demokritou

Abstract read
In one paragraph

Article in Environmental science. Nano, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  10. Toxicity, uptake, and nuclear translocation of ingested micro-nanoplastics in an in vitro model of the small intestinal epithelium.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios A SotiriouCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Ave., Boston, MA 02115, USA.
Dilpreet SinghCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Ave., Boston, MA 02115, USA.
Fang ZhangCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Ave., Boston, MA 02115, USA.
Wendel WohllebenCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Ave., Boston, MA 02115, USA ; BASF SE, Material Physics, 67056 Ludwigshafen, Germany.
Marie-Cecile G ChalbotDepartment of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Ilias G KavourasDepartment of Environmental and Occupational Health, College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Philip DemokritouCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Ave., Boston, MA 02115, USA.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

The proliferation of nano-enabled products (NEPs) renders human exposure to engineered nanomaterials (ENMs) inevitable. Over the last decade, the risk assessment paradigm for nanomaterials focused primarily on potential adverse effect of pristine, as-prepared ENMs. However, the physicochemical properties of ENMs may be drastically altered across their life-cycle (LC), especially when they are embedded in various NEP matrices. Of a particular interest is the end-of-life scenario by thermal decomposition. The main objective of the current study is to develop a standardized, versatile and reproducible methodology that allows for the systematic physicochemical and toxicological characterization of the NEP thermal decomposition. The developed methodology was tested for an industry-relevant NEP in order to verify its versatility for such LC investigations. Results are indicative of potential environmental health risks associated with waste from specific NEP families and prompt for the development of safer-by-design approaches and exposure control strategies.

Identifiers

PMID26200119
PMCPMC4508024

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.