Evidence map›Paper›PMID 26200111›Full record

Trial reportPloS one2015

Effects of Approach-Avoidance Training on the Extinction and Return of Fear Responses.

Angelos-Miltiadis Krypotos, Inna Arnaudova, Marieke Effting, Merel Kindt, Tom Beckers

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Midfrontal Theta Activity Is Sensitive to Approach-Avoidance Conflict.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  3. A Case for Translation From the Clinic to the Laboratory.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Angelos-Miltiadis KrypotosDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, the Netherlands.
Inna ArnaudovaDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, the Netherlands.
Marieke EfftingDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, the Netherlands.
Merel KindtDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, the Netherlands.
Tom BeckersDepartment of Clinical Psychology, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Brain and Cognition Center, Amsterdam, the Netherlands; Department of Psychology, KU Leuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesExposure therapy for anxiety involves confronting a patient with fear-evoking stimuli, a procedure based partially on Pavlovian extinction. Exposure and other extinction-based therapies usually lead to (partial) reduction of fear symptoms, but a substantial number of patients experience a return of fear after treatment. Here we tested whether the combination of fear extinction with modification of approach-avoidance tendencies using an Approach-Avoidance Task (AAT) would result in the further reduction of conditioned fear and/or help prevent return of fear after extinction.

methodsTwo groups of participants underwent a fear acquisition procedure during which pictures of one neutral object were sometimes paired with shock (CS+), whereas pictures of another neutral object were not (CS-). The next day, in a fear extinction procedure, both objects were presented without shock. During the subsequent joystick AAT, one group primarily pulled CS+ pictures towards themselves and pushed CS- pictures away from themselves; reversed contingencies applied for the other group.

resultsApproach training was effective in modifying conditioned action tendencies, with some evidence for transfer to a different approach/avoidance task. No group differences in subjective fear or physiological arousal were found during subsequent post- training and return-of-fear testing. LIMITATIONS: No reliable return-of-fear was observed in either group for either subjective or physiological fear measures.

conclusionsOur results suggest that approach training may be of limited value for enhancing the short- and long-term effects of extinction-based interventions.

Indexed as

Anxiety DisordersAvoidance LearningFearStress, PsychologicalAdultFemaleHumansImplosive TherapyMale

Identifiers

PMID26200111
PMCPMC4511792

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.