Evidence map›Paper›PMID 26200009›Full record

ArticleImmunity2015

Escaping Negative Selection: ILC You in the Gut.

Adam M Farkas, Ivaylo I Ivanov

Open access · bronzeAbstract readComment
In one paragraph

Article in Immunity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam M FarkasDepartment of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.
Ivaylo I IvanovDepartment of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA. Electronic address: ii2137@cumc.columbia.edu.
Columbia University Irving Medical Center · US

Funding

Role of intestinal commensal-induced Th17 cells and mucosal immunity in metabolic diseaseR01DK098378 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Ivaylo Ivanov Ivanov · 2013 to 2026
$6.5M
NIDDK NIH HHS R01 DK098378
6 · The paper itself

Abstract

How commensal-specific T cells are controlled in the periphery is poorly understood. In a recent issue of Science, Hepworth et al. (2015) show that ILC3s induce apoptosis of microbiota-specific CD4 T cells in a form of extrathymic negative selection.

Indexed as

Immunity, InnateAnimalsBacteriaCD4-Positive T-LymphocytesColonFemaleHistocompatibility Antigens Class IIHumansInflammatory Bowel DiseasesMaleHistocompatibility Antigens Class II

Identifiers

PMID26200009
PMCPMC4767161
OpenAlexW1480620136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.