ReviewBeilstein journal of nanotechnology2015
Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure.
Review in Beilstein journal of nanotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications.International journal of nanomedicine · 2018Article
- Synthetic approaches to nucleopeptides containing all four nucleobases, and nucleic acid-binding studies on a mixed-sequence nucleo-oligolysine.RSC advances · 2016Article
- Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability.RSC advances · 2016Article
- Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide.RSC advances · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The employment of molecular tools with nucleic acid binding ability to specifically control crucial cellular functions represents an important scientific area at the border between biochemistry and pharmaceutical chemistry. In this review we describe several molecular systems of natural or artificial origin, which are able to bind polyriboadenylic acid (poly(rA)) both in its single-stranded or structured forms. Due to the fundamental role played by the poly(rA) tail in the maturation and stability of mRNA, as well as in the initiation of the translation process, compounds able to bind this RNA tract, influencing the mRNA fate, are of special interest for developing innovative biomedical strategies mainly in the field of anticancer therapy.
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