ArticleJournal of neuroimmunology2015
Promiscuity of autoimmune responses to MBP after stroke.
Article in Journal of neuroimmunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Neuregulin-1 promotes early regenerative and autophagic responses after ischemic stroke via spatial proteomics.Frontiers in cellular neuroscience · 2026Article
- Inflammatory Responses After Ischemic Stroke.Seminars in immunopathology · 2022Review
- Immune markers are associated with cognitive performance in a multiethnic cohort: The Northern Manhattan Study.Brain, behavior, and immunity · 2021Article
- Silencing of microRNA-494 inhibits the neurotoxic Th1 shift via regulating HDAC2-STAT4 cascade in ischaemic stroke.British journal of pharmacology · 2020Article
- Autoimmunity After Ischemic Stroke and Brain Injury.Frontiers in immunology · 2019Review
- Review
- Emerging Role of Immunity in Cerebral Small Vessel Disease.Frontiers in immunology · 2018Review
- Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer's disease with cerebrovascular disease.Journal of neuroinflammation · 2017Article
- Point-of-Care-Testing in Acute Stroke Management: An Unmet Need Ripe for Technological Harvest.Biosensors · 2017Review
- The contribution of antibiotics, pneumonia and the immune response to stroke outcome.Journal of neuroimmunology · 2016Article
- Biomarkers for acute diagnosis and management of stroke in neurointensive care units.Brain circulationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In this study we examined Th1 and Th17 immune responses to rat myelin basic protein (MBP), bovine MBP, human MBP, MBP 68-86, MBP 63-81 and ovalbumin in Lewis rats to determine which MBP antigen is recognized following ischemic brain injury. Responses were compared to animals immunized to rat MBP. Data show that immune responses following immunization with rat MBP are promiscuous with cross reaction to MBP from other species. After stroke, few animals develop Th1 or Th17 responses to MBP, but when those responses occur, especially Th1 responses to rat MBP in the brain, they are predictive of worse stroke outcome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.