Evidence map›Paper›PMID 26198541›Full record

ArticleInternational journal of clinical pharmacy2015

Role of community pharmacists in the detection of potentially inappropriate benzodiazepines prescriptions for insomnia.

Silvana Anna Maria Urru, Luca Pasina, Paola Minghetti, Corrado Giua

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Article in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pitfalls of insomnia management in the elderly: A narrative review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Silvana Anna Maria UrruBiomedicine Sector, CRS4 Science and Technology Park Polaris, Piscina Manna, 09010, Pula, CA, Italy. silvanaurru@crs4.it.
Luca PasinaIRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
Paola MinghettiDepartment of Pharmaceutical Sciences, Università degli Studi di Milano, Milan, Italy.
Corrado GiuaDipartimento Scienze della Vita, Università degli Studi di Trieste, Trieste, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Milan · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe appropriate management of chronic insomnia is crucial and prescribing of hypnotic drugs is common. Regular and prolonged use of hypnotics should be avoided because of the risk of tolerance to effects, dependence and an increased risk of adverse events. In 2012, updated Beers criteria for potentially inappropriate medication in older adults suggested to avoid all benzodiazepines in older adults to treat insomnia. In addition, successful discontinuation may result in improvements on cognitive and psychomotor function, particularly in older people.

objectiveTo investigate the appropriateness of benzodiazepines prescription for insomnia and explore the role that community pharmacists can have in identifying signals of potential inappropriate drug prescriptions.

settingCommunity pharmacies in Italy.

methodThis is an observational study conducted in 8 community pharmacies. Each pharmacist was asked to interview a sample of patients with the prescriptions of at least one benzodiazepine and to complete a minimum data set collecting information about socio-demographic characteristics, drug indication, duration of drug prescription, number of hypnotic-drugs, previous attempt to drug-discontinuation, preference of patients about benzodiazepine withdrawal and modality of drug tapering. Main outcome measure Indications, treatment duration, dosage and drug discontinuation attempts and modalities.

resultsA total of 181 participants were interviewed. About half of respondents (n = 81) reported to be treated for insomnia and 62 % were elderly (mean age 68, range 27-93). Fifty-two patients (64 %) were on long term treatment (>3 years) while for thirteen patients (16 %) duration of treatment was comprised between 1 and 3 years. Thirty-three patients were in favour of benzodiazepine-discontinuation but in all cases discontinuation was unsuccessful.

conclusionUse of community pharmacy survey data allowed us to obtain information about incorrect management of insomnia and inappropriate benzodiazepines prescriptions. Stricter adherence to evidence-based guidelines is essential for a rational use of hypnotic and sedatives.

Indexed as

PharmacistsAdultAgedAged, 80 and overBenzodiazepinesCommunity Pharmacy ServicesCross-Sectional StudiesFemaleGuidelines as TopicHumansHypnotics and SedativesInappropriate PrescribingItalyMaleMiddle AgedSleep Initiation and Maintenance DisordersBenzodiazepinesHypnotics and SedativesBenzodiazepinesCommunity pharmaciesElderlyInsomniaItalyMedication appropriatenessPharmacoepidemiology

Identifiers

PMID26198541
OpenAlexW2141148178

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.