ArticleEndocrine2016
Smell-taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions.
Article in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 9 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta-Analysis.The Laryngoscope · 2026Pooled it
- Obesity, Olfaction and Cognition: A Systematic Review.Current obesity reports · 2025Pooled it
- Effects of weight change on taste function; a systematic review.Nutrition journal · 2023Pooled it
- A systematic review of the biological mediators of fat taste and smell.Physiological reviews · 2023Pooled it
- Psychophysical chemosensory dysfunction in eating disorders: a qualitative systematic review.Eating and weight disorders : EWD · 2022Pooled it
- Pooled it
- Olfaction is a Marker of Severity but Not Diagnosis in Anorexia Nervosa: a Systematic Review and Meta-Analysis.Neuropsychology review · 2020Pooled it
- Which Symptoms, Complaints and Complications of the Gastrointestinal Tract Occur in Patients With Eating Disorders? A Systematic Review and Quantitative Analysis.Frontiers in psychiatry · 2020Pooled it
- Taste sensitivity in anorexia nervosa: A systematic review.The International journal of eating disorders · 2018Pooled it
- Differences in Salivary Proteins as a Function of PROP Taster Status and Gender in Normal Weight and Obese Subjects.Molecules (Basel, Switzerland) · 2021Trial
- Insulin Resistance Is Associated with Reduced Food Odor Sensitivity across a Wide Range of Body Weights.Nutrients · 2020Trial
- Weight Loss, Dietary Preferences, and Reduction in the Sense of Smell with the Use of a Novel Nasal Device.Obesity facts · 2020Trial
- Gross Olfaction Before and After Laparoscopic Gastric Bypass.Obesity surgery · 2017Trial
- Olfactory dysfunction in obesity and type 2 diabetes: mechanistic insights from preclinical models.Diabetologia · 2026Review
- Food addiction as a mediator in the association between depression and body mass index among young adults in South Korea: a cross-sectional study.Journal of Korean biological nursing science · 2026Article
- Article
- GHSRs in the olfactory bulb suppress food motivation and promote exploration without altering spatial memory in male mice.Journal of neuroendocrinology · 2025Article
- Beyond Hunger: The Structure, Signaling, and Systemic Roles of Ghrelin.International journal of molecular sciences · 2025Review
- Mediating effect of food disgust between depression/anxiety and avoidant restrictive eating.Journal of eating disorders · 2025Article
- Differences in Perceived Versus Actual Sensory Perception in Avoidant/Restrictive Food Intake Disorder.The International journal of eating disorders · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 12 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) The objective of this study is to analyze differences in smell-taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through "Sniffin' Sticks" and "Taste Strips," respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.