Evidence map›Paper›PMID 26198305›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2015

Big biomedical data as the key resource for discovery science.

Arthur W Toga, Ian Foster, Carl Kesselman, Ravi Madduri, Kyle Chard, Eric W Deutsch, Nathan D Price, Gustavo Glusman, Benjamin D Heavner, Ivo D Dinov and 4 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Functional Neuroimaging in the New Era of Big Data.Genomics, proteomics & bioinformatics · 2019
    Review
  10. Article
  11. Personalized medicine in breast cancer: pharmacogenomics approaches.Pharmacogenomics and personalized medicine · 2019
    Review
  12. Article
  13. The role of ethics in data governance of large neuro-ICT projects.Journal of the American Medical Informatics Association : JAMIA · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Exploring completeness in clinical data research networks with DQe-c.Journal of the American Medical Informatics Association : JAMIA · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Arthur W TogaLaboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA toga@loni.usc.edu.
Ian FosterComputation Institute, University of Chicago and Argonne National Laboratory, Chicago, IL, USA.
Carl KesselmanInformation Sciences Institute, University of Southern California, Los Angeles, CA, USA.
Ravi MadduriComputation Institute, University of Chicago and Argonne National Laboratory, Chicago, IL, USA.
Kyle ChardComputation Institute, University of Chicago and Argonne National Laboratory, Chicago, IL, USA.
Eric W DeutschInstitute for Systems Biology, Seattle, WA, USA.
Nathan D PriceInstitute for Systems Biology, Seattle, WA, USA.
Gustavo GlusmanInstitute for Systems Biology, Seattle, WA, USA.
Benjamin D HeavnerInstitute for Systems Biology, Seattle, WA, USA.
Ivo D DinovStatistics Online Computational Resource (SOCR), UMSN, University of Michigan, Ann Arbor, MI, USA.
Joseph AmesLaboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA.
John Van HornLaboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA.
Roger KramerInstitute for Systems Biology, Seattle, WA, USA.
Leroy HoodInstitute for Systems Biology, Seattle, WA, USA.

Funding

TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
TrainingU54EB020406 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOGA, ARTHUR W · 2014 to 2018
$12.5M
Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
NIBIB NIH HHS 1U54EB020406-01NIBIB NIH HHS P41 EB015922NIBIB NIH HHS U54 EB020406NINDS NIH HHS P50 NS091856
6 · The paper itself

Abstract

Modern biomedical data collection is generating exponentially more data in a multitude of formats. This flood of complex data poses significant opportunities to discover and understand the critical interplay among such diverse domains as genomics, proteomics, metabolomics, and phenomics, including imaging, biometrics, and clinical data. The Big Data for Discovery Science Center is taking an "-ome to home" approach to discover linkages between these disparate data sources by mining existing databases of proteomic and genomic data, brain images, and clinical assessments. In support of this work, the authors developed new technological capabilities that make it easy for researchers to manage, aggregate, manipulate, integrate, and model large amounts of distributed data. Guided by biological domain expertise, the Center's computational resources and software will reveal relationships and patterns, aiding researchers in identifying biomarkers for the most confounding conditions and diseases, such as Parkinson's and Alzheimer's.

Indexed as

Biomedical ResearchDatasets as TopicNeurosciencesHumansNational Institutes of Health (U.S.)Translational Research, BiomedicalUnited StatesAlzheimer's disease (ID)analyticsBD2Kbigbig databiomedicaldatadiscoverydiscovery scienceParkinson's diseaseresourcescience, neuroscience (ja)

Identifiers

PMID26198305
PMCPMC5009918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.