ArticlePlant physiology2015
Mapping of a Cellulose-Deficient Mutant Named dwarf1-1 in Sorghum bicolor to the Green Revolution Gene gibberellin20-oxidase Reveals a Positive Regulatory Association between Gibberellin and Cellulose Biosynthesis.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 36 citations in OpenAlex.
- Comparative transcriptome analysis provides insights into the dwarfing mechanism of pear trees.BMC genomic data · 2026Article
- Recent advances in breeding systems and their improvement in forage crops.Molecular biology reports · 2025Review
- Identifying genetic determinants of forage sorghum [Sorghum bicolor (Moench)] adaptation through GWAS.BMC plant biology · 2024Article
- Enhanced phytoremediation of cadmium-contaminated soil using chelating agents and plant growth regulators: effect and mechanism.Royal Society open science · 2024Article
- A gibberellin-deficient maize mutant exhibits altered plant height, stem strength and drought tolerance.Plant cell reports · 2023Article
- Genetic Determinants of Biomass in CFrontiers in plant science · 2022Review
- Review
- Gibberellin induced transcription factor bZIP53 regulates CesA1 expression in maize kernels.PloS one · 2021Article
- Associations between phytohormones and cellulose biosynthesis in land plants.Annals of botany · 2020Review
- Rhizobacterial species richness improves sorghum growth and soil nutrient synergism in a nutrient-poor greenhouse soil.Scientific reports · 2020Article
- Plant cell wall integrity maintenance in model plants and crop species-relevant cell wall components and underlying guiding principles.Cellular and molecular life sciences : CMLS · 2020Review
- MYB43 in Oilseed Rape (Genes · 2020Article
- Transcriptional Regulation of Sorghum Stem Composition: Key Players Identified Through Co-expression Gene Network and Comparative Genomics Analyses.Frontiers in plant science · 2020Article
- Biochemical and physiological flexibility accompanies reduced cellulose biosynthesis in BrachypodiumAoB PLANTS · 2019Article
- Effect of 1-aminocyclopropane-1-carboxylic acid (ACC)-induced ethylene on cellulose synthase A (CesA) genes in flax (Linum usitatissimum L. 'Nike') seedlings.Genes & genomics · 2018Article
- GAFunctional & integrative genomics · 2018Article
- Article
- Whole-Genome Sequence Accuracy Is Improved by Replication in a Population of Mutagenized Sorghum.G3 (Bethesda, Md.) · 2018Article
- Article
- Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines.G3 (Bethesda, Md.) · 2017Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Here, we show a mechanism for expansion regulation through mutations in the green revolution gene gibberellin20 (GA20)-oxidase and show that GAs control biosynthesis of the plants main structural polymer cellulose. Within a 12,000 mutagenized Sorghum bicolor plant population, we identified a single cellulose-deficient and male gametophyte-dysfunctional mutant named dwarf1-1 (dwf1-1). Through the Sorghum propinquum male/dwf1-1 female F2 population, we mapped dwf1-1 to a frameshift in GA20-oxidase. Assessment of GAs in dwf1-1 revealed ablation of GA. GA ablation was antagonistic to the expression of three specific cellulose synthase genes resulting in cellulose deficiency and growth dwarfism, which were complemented by exogenous bioactive gibberellic acid application. Using quantitative polymerase chain reaction, we found that GA was positively regulating the expression of a subset of specific cellulose synthase genes. To cross reference data from our mapped Sorghum sp. allele with another monocotyledonous plant, a series of rice (Oryza sativa) mutants involved in GA biosynthesis and signaling were isolated, and these too displayed cellulose deficit. Taken together, data support a model whereby suppressed expansion in green revolution GA genes involves regulation of cellulose biosynthesis.
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