Evidence map›Paper›PMID 26197888›Full record

Observational studyBMC cardiovascular disorders2015

Risk factors and in-hospital outcome of acute ST segment elevation myocardial infarction in young Bangladeshi adults.

Mohammad Azizul Karim, Abdullah Al Shafi Majumder, Khandaker Qamrul Islam, Muhammad Badrul Alam, Makhan Lal Paul, Mohammad Shafiqul Islam, Kamrun N Chowdhury, Sheikh Mohammed Shariful Islam

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Mohammad Azizul KarimNational Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh. azizulkarim74@yahoo.com.
Abdullah Al Shafi MajumderNational Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh. m.abdullaalshafi@yahoo.com.
Khandaker Qamrul IslamNational Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh. qislam@gmail.com.
Muhammad Badrul AlamRangpur Medical College, Rangpur, Bangladesh. Mbadrulalam@yahoo.com.
Makhan Lal PaulCentral Medical College, Comilla, Bangladesh. drmpaul@gmail.com.
Mohammad Shafiqul IslamTrishal Health Complex, Mymensingh, Bangladesh. Shafiqcard@yahoo.com.
Kamrun N ChowdhuryDepartment of Epidemiology, National Centre for Control of Rheumatic Fever and Heart Disease, Dhaka, Bangladesh. kamrun.nccrfhd@yahoo.com.
Sheikh Mohammed Shariful IslamInternational Center for Diarrhoeal Disease Research, Bangladesh, Center for Control of Chronic Diseases, Dhaka, Bangladesh. shariful.islam@icddrb.org.
National Institute of Cardiovascular Diseases · BDInternational Centre for Diarrhoeal Disease Research · BDComilla Medical College · BDDinajpur Medical College · BDNational Institute of Cardiovascular Diseases · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSouth Asians have a higher overall incidence rate and younger age of onset for acute myocardial infarction (AMI) compared to Western populations. However, limited information is available on the association of preventable risk factors and outcomes of AMI among young individuals in Bangladesh. The aim of this study was to determine the risk factors and in-hospital outcome of AMI among young (age ≤40 years) adults in Bangladesh.

methodsWe conducted a prospective observational study among consecutive 50 patients aged ≤40 years and 50 patients aged >40 years with acute ST Segment Elevation Myocardial Infarction (STEMI) and followed-up in-hospital at the National Institute of Cardiovascular Diseases (NICVD). Clinical characteristics, biochemical findings, diet, echocardiography and in-hospital outcomes were compared between the two groups. Multivariate logistic regression was performed to assess the association between risk factors and in-hospital outcome in young patients adjusting for other confounding variables.

resultsThe mean age of the young and older patient groups was 36.5 ± 4.6 years and 57.0 ± 9.1 years respectively. Male sex (OR 3.4, 95 % CI 1.2 - 9.75), smoking (OR 2.4, 95 % CI 1.04 - 5,62), family history of MI (OR 2.4, 95 % CI 1.11 - 5,54), homocysteine (OR 1.2, 95 % CI 1.08 - 1.36), eating rice ≥2 times daily (OR 3.5, 95 % CI 1.15 - 10.6) and eating beef (OR 4.5, 95 % CI 1.83 - 11.3) were significantly associated with the risk of AMI in the young group compared to older group. In multivariate analysis, older patients had significantly greater chance of developing heart failure (OR 7.5, 95 % CI 1.51 to 37.31), re-infarction (OR 7.0, 95 % CI 1.08 - 45.72), arrhythmia (OR 15.3, 95 % CI 2.69 - 87.77) and cardiogenic shock (OR 69.0, 95 % CI 5.81 - 85.52) than the younger group.

conclusionYounger AMI patients have a different risk profile and better in-hospital outcomes compared to the older patients. Control of preventable risk factors such as smoking, unhealthy diet, obesity and dyslipidemia should be reinforced at an early age in Bangladesh.

Indexed as

AdultAgedAge FactorsBangladeshElectrocardiographyFeeding BehaviorFemaleHospital MortalityHumansLength of StayMaleMiddle AgedMyocardial InfarctionPrognosisProspective StudiesRisk Factors

Identifiers

PMID26197888
PMCPMC4509563
OpenAlexW1629905090

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.