Evidence map›Paper›PMID 26197812›Full record

ArticleBMC cardiovascular disorders2015

Functional capacity and heart rate response: associations with nocturnal hypertension.

Paul Ritvo, Leslie E Stefanyk, Saam Azargive, Slobodan Stojanovic, Faye Stollon, Juda Habot, Yaariv Khaykin, Terry Fair, Meysam Pirbaglou

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Paul RitvoSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. pritvo@yorku.ca.
Leslie E StefanykSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. leslie.stefanyk@guelphhumber.ca.
Saam AzargiveSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. sazargiv@yorku.ca.
Slobodan StojanovicSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. slobo74@yorku.ca.
Faye StollonSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. fstollon@yorku.ca.
Juda HabotDivision of Cardiology, Southlake Regional Health Centre, Newmarket, ON, Canada. habot@rogers.com.
Yaariv KhaykinDivision of Cardiology, Southlake Regional Health Centre, Newmarket, ON, Canada. y.khaykin@utoronto.ca.
Terry FairDivision of Cardiology, Southlake Regional Health Centre, Newmarket, ON, Canada. tfair@southlakeregional.org.
Meysam PirbaglouSchool of Kinesiology and Health Science, York University, Toronto, ON, Canada. meyir@yorku.ca.
York University · CASouthlake Regional Health Center · CACancer Care Ontario · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbsences of normative, 10-20 % declines in blood pressure (BP) at night, termed nocturnal non-dipping, are linked to increased cardiovascular mortality risks. Current literature has linked these absences to psychological states, hormonal imbalance, and disorders involving hyper-arousal. This study focuses on evaluating associations between nocturnal non-dipping and indices of functional cardiac capacity and fitness.

methodsThe current study was a cross-sectional evaluation of the associations between physical capacity variables e.g. Metabolic Equivalent (MET) and Maximum Heart Rate (MHR), Heart rate reserve (HRR), and degree of reduction in nocturnal systolic blood pressure (SBP) or diastolic blood pressure (DBP), also known as 'dipping'. The study sample included 96 cardiac patient participants assessed for physical capacity and ambulatory blood pressure monitoring. In addition to evaluating differences between groups on nocturnal BP 'dipping', physical capacity, diagnoses, and medications, linear regression analyses were used to evaluate potential associations between nocturnal SBP and DBP 'dipping', and physical capacity indices.

results45 males and 14 females or 61.5 % of 96 consented participants met criteria as non-dippers (<10 % drop in nocturnal BP). Although non-dippers were older (p = .01) and had a lower maximum heart rate during the Bruce stress test (p = .05), dipping was only significantly associated with Type 2 Diabetes co-morbidity and was not associated with type of medication. Within separate linear regression models controlling for participant sex, MHR (β = 0.26, p = .01, R(2) = .06), HRR (β = 0. 19, p = .05, R(2) = .05), and METs (β = 0.21, p = .04, R(2) = .04) emerged as significant but small predictors of degree of nighttime SBP dipping. Similar relationships were not observed for DBP.

conclusionsSince the variables reflecting basic heart function and fitness (MHR and METs), did not account for appreciable variances in nighttime BP, nocturnal hypertension appears to be a complex, multi-faceted phenomena.

Indexed as

Heart RatePhysical FitnessAgedBlood Pressure Monitoring, AmbulatoryCircadian RhythmCross-Sectional StudiesExercise TestExercise ToleranceFemaleHumansHypertensionMaleMiddle Aged

Identifiers

PMID26197812
PMCPMC4511245
OpenAlexW1660338335

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.