ArticleMolecules (Basel, Switzerland)2015
New cembranoid diterpenes from the cultured octocoral Nephthea columnaris.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Diterpenoids of Marine Organisms: Isolation, Structures, and Bioactivities.Marine drugs · 2025Review
- GenusMarine drugs · 2023Review
- Pectin Nanoparticle-Loaded Soft CoralPharmaceuticals (Basel, Switzerland) · 2023Article
- Towards Sustainable Medicinal Resources through Marine Soft Coral Aquaculture: Insights into the Chemical Diversity and the Biological Potential.Marine drugs · 2022Review
- Review
- Sterols from the Octocoral Nephthea columnaris.Marine drugs · 2017Article
- Semisynthetic and SAR Studies of Amide Derivatives of Neocrotocembraneic Acid as Potential Antitumor Agents.Molecules (Basel, Switzerland) · 2016Article
- New Cembrane-Type Diterpenoids from the South China Sea Soft Coral Sarcophyton ehrenbergi.Molecules (Basel, Switzerland) · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two new 15-hydroxycembranoid diterpenes, 2β-hydroxy-7β,8α-epoxynephthenol (1) and 2β-hydroxy-11α,12β-epoxynephthenol (2), were isolated from extracts of the octocoral Nephthea columnaris along with a new natural cembrane, epoxynephthenol (3) and a known sterol, nephalsterol A (4). The structures of cembranes 1-3 were elucidated by spectroscopic methods and comparison of the spectroscopic data with those of related analogues. The cytotoxicity of metabolites 1-4 against a panel of tumor cells is also described.
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