ArticleEmerging infectious diseases2015
Influenza A Viruses of Human Origin in Swine, Brazil.
Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 64 citations in OpenAlex.
- Passive surveillance for Influenza A virus among swine, Brazil, 2009-2023.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Zoonotic transmission of novel Influenza A variant viruses detected in Brazil during 2020 to 2023.Nature communications · 2024Article
- Review
- Swine influenza A virus: challenges and novel vaccine strategies.Frontiers in cellular and infection microbiology · 2024Review
- Novel introductions of human-origin H3N2 influenza viruses in swine, Chile.Frontiers in veterinary science · 2024Article
- A polyvalent virosomal influenza vaccine induces broad cellular and humoral immunity in pigs.Virology journal · 2023Article
- Introductions of Human-Origin Seasonal H3N2, H1N2 and Pre-2009 H1N1 Influenza Viruses to Swine in Brazil.Viruses · 2023Article
- Human-to-swine introductions and onward transmission of 2009 H1N1 pandemic influenza viruses in Brazil.Frontiers in microbiology · 2023Article
- Antigenic characterization of influenza and SARS-CoV-2 viruses.Analytical and bioanalytical chemistry · 2022Review
- Review of genome sequencing technologies in molecular characterization of influenza A viruses in swine.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Zooming in on the molecular characteristics of swine influenza virus circulating in Colombia before and after the H1N1pdm09 virus.Frontiers in veterinary science · 2022Article
- Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Ubiquitous influenza A virus in Chilean swine before the H1N1pdm09 introduction.Transboundary and emerging diseases · 2021Article
- Swine Influenza A Viruses and the Tangled Relationship with Humans.Cold Spring Harbor perspectives in medicine · 2021Review
- Evaluation of two multiplex RT-PCR assays for detection and subtype differentiation of Brazilian swine influenza viruses.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide.Pathogens (Basel, Switzerland) · 2020Review
- Interspecies Transmission of Reassortant Swine Influenza A Virus Containing Genes from Swine Influenza A(H1N1)pdm09 and A(H1N2) Viruses.Emerging infectious diseases · 2020Article
- Influenza A Virus in Swine: Epidemiology, Challenges and Vaccination Strategies.Frontiers in veterinary science · 2020Review
- Re-evaluation of the evolution of influenza H1 viruses using direct PCA.Scientific reports · 2019Article
- Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia.Emerging microbes & infections · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American countries. Although Brazil has one of the largest swine populations in the world, influenza was not thought to be endemic in Brazil's swine until the major outbreaks of influenza A(H1N1)pdm09 in 2009. Through phylogenetic analysis of whole-genome sequences of influenza viruses of the H1N1, H1N2, and H3N2 subtypes collected in swine in Brazil during 2009-2012, we identified multiple previously uncharacterized influenza viruses of human seasonal H1N2 and H3N2 virus origin that have circulated undetected in swine for more than a decade. Viral diversity has further increased in Brazil through reassortment between co-circulating viruses, including A(H1N1)pdm09. The circulation of multiple divergent hemagglutinin lineages challenges the design of effective cross-protective vaccines and highlights the need for additional surveillance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.