ArticleMetabolomics : Official journal of the Metabolomic Society2015
An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data.
Article in Metabolomics : Official journal of the Metabolomic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- In Vitro Digestion Influences Bioactive Compound Profiles, Antioxidant Activity, and Free Amino Acid Release in Plant-Based Milk Alternatives.Foods (Basel, Switzerland) · 2026Article
- Integrated metabolomic, cytotoxic, and computational investigation of Caralluma tuberculata extract in breast cancer cells.Scientific reports · 2026Article
- Enhancing detection of low‑abundance metabolites in proton NMR through band‑selective suppression and presaturation.Natural products and bioprospecting · 2026Article
- Interpretation of Health-Smart Home Data and Implications for Clinical Decision-Making: Inductive Content Analysis.JMIR nursing · 2025Article
- Elevated levels of butyric acid in the jejunum of an animal model of broiler chickens: from early onset of Clostridium perfringens infection to clinical disease of necrotic enteritis.Journal of animal science and biotechnology · 2024Article
- Article
- Data-Driven Characterization of Metabolome Reprogramming during Early Development of Sorghum Seedlings.Metabolites · 2024Article
- Phenotypic and metabolomic characteristics of mouse models of metabolic associated steatohepatitis.Biomarker research · 2024Article
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- Diversity of enterobacterales in sediments of lagoons with fish farming activity and analysis of antibiotic resistance.Toxicology reports · 2023Article
- The use of ecological analytical tools as an unconventional approach for untargeted metabolomics data analysis: the case of Cecropia obtusifolia and its adaptive responses to nitrate starvation.Functional & integrative genomics · 2022Article
- Sensory and metabolite migration from tilapia skin to soup during the boiling process: fast and then slow.NPJ science of food · 2022Article
- Targeted and Untargeted Mass Spectrometry-Based Metabolomics for Chemical Profiling of Three Coffee Species.Molecules (Basel, Switzerland) · 2022Article
- Investigation of the individual human sulfatome in plasma and urine samples reveals an age-dependency.RSC advances · 2021Article
- Metabolic Analysis ofFrontiers in bioengineering and biotechnology · 2021Article
- Development of an Online Health Care Assessment for Preventive Medicine: A Machine Learning Approach.Journal of medical Internet research · 2020Article
- Elucidating the interaction of kansui and licorice by comparative plasma/tissue metabolomics and a heatmap with relative fold change.Journal of pharmaceutical analysis · 2019Article
- Metabolomics ofMolecules (Basel, Switzerland) · 2018Article
- A Metabolomic and HPLC-MS/MS Analysis of the Foliar Phenolics, Flavonoids and Coumarins of theMolecules (Basel, Switzerland) · 2018Article
- Antioxidant Activity of the Lignins Derived from Fluidized-Bed Fast Pyrolysis.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Heat maps are a commonly used visualization tool for metabolomic data where the relative abundance of ions detected in each sample is represented with color intensity. A limitation of applying heat maps to global metabolomic data, however, is the large number of ions that have to be displayed and the lack of information provided about important metabolomic parameters such as m/z and retention time. Here we address these challenges by introducing the interactive cluster heat map in the data-processing software XCMS Online. XCMS Online (xcmsonline.scripps.edu) is a cloud-based informatic platform designed to process, statistically evaluate, and visualize mass-spectrometry based metabolomic data. An interactive heat map is provided for all data processed by XCMS Online. The heat map is clickable, allowing users to zoom and explore specific metabolite metadata (EICs, Box-and-whisker plots, mass spectra) that are linked to the METLIN metabolite database. The utility of the XCMS interactive heat map is demonstrated on metabolomic data set generated from different anatomical regions of the mouse brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.