ArticleJournal of stem cells & regenerative medicine2015
Tendinopathies and platelet-rich plasma (PRP): from pre-clinical experiments to therapeutic use.
Article in Journal of stem cells & regenerative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Use of Platelet-Rich Plasma for De Quervain's Tenosynovitis:Saudi medical journal · 2026Pooled it
- Effectiveness of Exercise Treatments with or without Adjuncts for Common Lower Limb Tendinopathies: A Living Systematic Review and Network Meta-analysis.Sports medicine - open · 2023Pooled it
- Trial
- Effect of intralesional platelet-rich plasma (PRP) treatment on clinical and ultrasonographic parameters in equine naturally occurring superficial digital flexor tendinopathies - a randomized prospective controlled clinical trial.BMC veterinary research · 2016Trial
- Rehabilitation and return to activity after platelet-rich plasma injections in chronic tendinopathies: Consensus from international experts.PM & R : the journal of injury, function, and rehabilitation · 2026Review
- Review
- Denervation procedure of the lateral epicondyle for refractory lateral epicondylitis.JSES international · 2025Article
- Clinical implications of reconsideration of enthesitis/enthesopathy/enthesial erosion, as tendon attachment-localized avulsions and stress fracture equivalents.World journal of orthopedics · 2024Article
- EXPLORING THE FEASIBILITY OF PLATELET-RICH PLASMA INJECTIONS FOR INTERVERTEBRAL DISCOPATHY: A PILOT STUDY.Journal of rehabilitation medicine. Clinical communications · 2024Article
- Impact of autologous platelet-rich plasma therapy vs. hyaluronic acid on synovial fluid biomarkers in knee osteoarthritis: a randomized controlled clinical trial.Frontiers in medicine · 2023Article
- Chinese Consensus on Insertional Achilles Tendinopathy.Orthopaedic journal of sports medicine · 2019Article
- Achilles Tendinopathy and Associated Disorders.Foot & ankle orthopaedics · 2019Review
- Effects of Allogeneic Platelet-Rich Plasma (PRP) on the Healing Process of Sectioned Achilles Tendons of Rats: A Methodological Description.Journal of visualized experiments : JoVE · 2018Article
- Comparison of Effects of Leukocyte-Rich and Leukocyte-Poor Platelet-Rich Plasma on Pain and Functionality in Patients With Lateral Epicondylitis.Archives of rheumatology · 2018Article
- Enhanced proliferation and migration capability of epidermal stem cells by PRP and PDGF stimulation.International journal of clinical and experimental pathology · 2017Article
- Responders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis.BioMed research international · 2017Review
- Achilles Tendinopathy: Current Concepts about the Basic Science and Clinical Treatments.BioMed research international · 2016Review
- Hyaluronic acid and tendon lesions.Muscles, ligaments and tendons journalReview
- Role of platelet rich plasma in rotator cuff tendinopathy- clinical application and review of literature.Journal of clinical orthopaedics and traumaReview
- Efficacy of autologous leukocyte-reduced platelet-rich plasma therapy for patellar tendinopathy in a rat treadmill model.Muscles, ligaments and tendons journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe restorative properties of platelets, through the local release of growth factors, are used in various medical areas. This article reviews fundamental and clinical research relating to platelet-rich plasma applied to tendinous lesions. MATERIALS AND
methodArticles in French and English, published between 1 January 2012 and 31 December 2014. dealing with PRP and tendons were searched for using the Medline and Scopus data bases.
resultsForty-seven articles were identified which addressed pre-clinical and clinical studies: 27 relating to in vitro and in vivo animal studies and 20 relating to human studies. Of these, five addressed lateral epicondylitis, two addressed rotator cuff tendinopathies, ten dealt with patellar tendinopathies and three looked at Achilles tendinopathies.
conclusionsThe majority of pre-clinical studies show that PRP stimulates the tendon's healing process. However, clinical series remain more controversial and level 1, controlled, randomised studies are still needed.
Indexed as
Identifiers
26195890PMC4498322What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.