ArticleJournal of experimental botany2015
Expanding the repertoire of secretory peptides controlling root development with comparative genome analysis and functional assays.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45 citing papers in PubMed, 94 citations in OpenAlex.
- A transcriptional atlas of early Arabidopsis seed development suggests mechanisms for inter-tissue coordination.Nature plants · 2026Article
- SPlant biotechnology journal · 2026Article
- Several plant self-incompatibility systems may be controlled by atypical receptor-ligand interactions.The Plant journal : for cell and molecular biology · 2026Review
- Identification of the Casparian strip integrity factor (CIF) gene family in Brassica napus and functional prediction of mature CIF small peptides.BMC plant biology · 2025Article
- Peptides and Reactive Oxygen Species Regulate Root Development.International journal of molecular sciences · 2025Review
- Genome-wide exploration and characterization of the RALFs and analysis of its role in peanut (Arachis hypogaea L.).BMC plant biology · 2025Article
- Unraveling a Small Secreted Peptide SUBPEP3 That Positively Regulates Salt-Stress Tolerance inInternational journal of molecular sciences · 2024Article
- Subtilases: a major prospect to the genome editing in horticultural crops.Frontiers in plant science · 2024Review
- Genetic regulation of lateral root development.Plant signaling & behavior · 2023Review
- Specificity models in MAPK cascade signaling.FEBS open bio · 2023Review
- The CLE33 peptide represses phloem differentiation via autocrine and paracrine signaling in Arabidopsis.Communications biology · 2023Article
- Annotated genome sequence of a fast-growing diploid clone of red alder (Alnus rubra Bong.).G3 (Bethesda, Md.) · 2023Article
- Molecular Mechanisms of Regulation of Root Development by Plant Peptides.Plants (Basel, Switzerland) · 2023Review
- Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3.eLife · 2022Article
- Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana.The New phytologist · 2022Article
- Comprehensive analysis of peptide-coding genes and initial characterization of an LRR-only microprotein inFrontiers in plant science · 2022Article
- Insight into early diversification of leucine-rich repeat receptor-like kinases provided by the sequenced moss and hornwort genomes.Plant molecular biology · 2021Article
- The sequenced genomes of nonflowering land plants reveal the innovative evolutionary history of peptide signaling.The Plant cell · 2021Review
- Auxin-Regulated Lateral Root Organogenesis.Cold Spring Harbor perspectives in biology · 2021Review
- Advances and perspectives in discovery and functional analysis of small secreted proteins in plants.Horticulture research · 2021Review
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant genomes encode numerous small secretory peptides (SSPs) whose functions have yet to be explored. Based on structural features that characterize SSP families known to take part in postembryonic development, this comparative genome analysis resulted in the identification of genes coding for oligopeptides potentially involved in cell-to-cell communication. Because genome annotation based on short sequence homology is difficult, the criteria for the de novo identification and aggregation of conserved SSP sequences were first benchmarked across five reference plant species. The resulting gene families were then extended to 32 genome sequences, including major crops. The global phylogenetic pattern common to the functionally characterized SSP families suggests that their apparition and expansion coincide with that of the land plants. The SSP families can be searched online for members, sequences and consensus (http://bioinformatics.psb.ugent.be/webtools/PlantSSP/). Looking for putative regulators of root development, Arabidopsis thaliana SSP genes were further selected through transcriptome meta-analysis based on their expression at specific stages and in specific cell types in the course of the lateral root formation. As an additional indication that formerly uncharacterized SSPs may control development, this study showed that root growth and branching were altered by the application of synthetic peptides matching conserved SSP motifs, sometimes in very specific ways. The strategy used in the study, combining comparative genomics, transcriptome meta-analysis and peptide functional assays in planta, pinpoints factors potentially involved in non-cell-autonomous regulatory mechanisms. A similar approach can be implemented in different species for the study of a wide range of developmental programmes.
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