Evidence map›Paper›PMID 26195686›Full record

ArticleAnnals of family medicine

Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable.

Sean P David, Samuel G Johnson, Adam C Berger, W Gregory Feero, Sharon F Terry, Larry A Green, Robert L Phillips, Geoffrey S Ginsburg

Abstract read
In one paragraph

Article in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Primary care providers' experiences with and perceptions of personalized genomic medicine.Canadian family physician Medecin de famille canadien · 2016
    Article
  15. Article
  16. Article
  17. A Use Case to Support Precision Medicine for Frequently Hospitalized Older Adults with Polypharmacy.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sean P DavidDepartment of Medicine, Stanford University School of Medicine, Palo Alto, California Roundtable on Translating Genomic-Based Research for Health, Institute of Medicine (IOM) of the National Academies spdavid@stanford.edu.
Samuel G JohnsonRoundtable on Translating Genomic-Based Research for Health, Institute of Medicine (IOM) of the National Academies Applied Pharmacogenomics, Kaiser-Permanente Colorado, Aurora, Colorado Department of Clinical Pharmacy, University of Colorado, Denver, Colorado.
Adam C BergerApplied Pharmacogenomics, Kaiser-Permanente Colorado, Aurora, Colorado.
W Gregory FeeroApplied Pharmacogenomics, Kaiser-Permanente Colorado, Aurora, Colorado Maine-Dartmouth Family Medicine Residency Program, Augusta, Maine.
Sharon F TerryRoundtable on Translating Genomic-Based Research for Health, Institute of Medicine (IOM) of the National Academies Genetic Alliance, Washington, DC.
Larry A GreenDepartment of Family Medicine, University of Colorado, Denver, Colorado.
Robert L PhillipsAmerican Board of Family Medicine, Lexington, Kentucky.
Geoffrey S GinsburgRoundtable on Translating Genomic-Based Research for Health, Institute of Medicine (IOM) of the National Academies Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, North Carolina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic research has generated much new knowledge into mechanisms of human disease, with the potential to catalyze novel drug discovery and development, prenatal and neonatal screening, clinical pharmacogenomics, more sensitive risk prediction, and enhanced diagnostics. Genomic medicine, however, has been limited by critical evidence gaps, especially those related to clinical utility and applicability to diverse populations. Genomic medicine may have the greatest impact on health care if it is integrated into primary care, where most health care is received and where evidence supports the value of personalized medicine grounded in continuous healing relationships. Redesigned primary care is the most relevant setting for clinically useful genomic medicine research. Taking insights gained from the activities of the Institute of Medicine (IOM) Roundtable on Translating Genomic-Based Research for Health, we apply lessons learned from the patient-centered medical home national experience to implement genomic medicine in a patient-centered, learning health care system.

Indexed as

GenomicsPatient-Centered CarePrecision MedicineHumansNational Academies of Science, Engineering, and Medicine, U.S., Health and Medicine DivisionTranslational Research, BiomedicalUnited Statesclinical implementation sciencegenomicspersonalized medicineprecision medicineprimary health care

Identifiers

PMID26195686
PMCPMC4508182

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.