Evidence map›Paper›PMID 26195536›Full record

ArticlePediatrics2015

Choosing Wisely in Newborn Medicine: Five Opportunities to Increase Value.

Timmy Ho, Dmitry Dukhovny, John A F Zupancic, Don A Goldmann, Jeffrey D Horbar, DeWayne M Pursley

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
34.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 168 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Prospective economic evaluation alongside the non-invasive ventilation trial.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Trial
  4. Apnea of prematurity and caffeine pharmacokinetics: potential impact on hospital discharge.Journal of perinatology : official journal of the California Perinatal Association · 2016
    Trial
  5. Standardizing early cerebral palsy detection in high-risk infants: reducing age at diagnosis through a quality improvement initiative.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Article
  12. Article
  13. Review
  14. Transforming neonatal care with artificial intelligence: challenges, ethical consideration, and opportunities.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
  15. Article
  16. Article
  17. The association of regional perinatal risk factors and neonatal intensive care capacity for Military Health System-insured newborns.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Timmy HoDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Medicine, Boston Children's Hospital, Boston, Massachusetts; Institute for Healthcare Improvement, Cambridge, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts;
Dmitry DukhovnyDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Pediatrics, Oregon Health and Science University, Portland, Oregon;
John A F ZupancicDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts;
Don A GoldmannDepartment of Medicine, Boston Children's Hospital, Boston, Massachusetts; Institute for Healthcare Improvement, Cambridge, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts;
Jeffrey D HorbarDepartment of Pediatrics, University of Vermont, Burlington, Vermont; and Vermont Oxford Network, Burlington, Vermont.
DeWayne M PursleyDepartment of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Department of Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; dpursley@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · USBoston Children's Hospital · USHarvard University · USInstitute for Healthcare Improvement · USVermont Oxford Network · US

Funding

Training in Child Health Services Research and Implementation ScienceT32HS000063 · AHRQ · CHILDREN'S HOSPITAL BOSTON · PI GARABEDIAN, LAURA FADEN, WALSH, KATHLEEN ELIZABETH · 1994 to 2024
$7.6M
AHRQ HHS 5T32HS000063-21AHRQ HHS T32 HS000063
6 · The paper itself

Abstract

backgroundThe use of unnecessary tests and treatments contributes to health care waste. The "Choosing Wisely" campaign charges medical societies with identifying such items. This report describes the identification of 5 tests and treatments in newborn medicine.

methodsA national survey identified candidate tests and treatments. An expert panel of 51 individuals representing 28 perinatal care organizations narrowed the list over 3 rounds of a modified Delphi process. In the final round, the panel was provided with Grading of Recommendation, Assessment, Development and Evaluation (GRADE) literature summaries of the top 12 tests and treatments.

resultsA total of 1648 candidate tests and 1222 treatments were suggested by 1047 survey respondents. After 3 Delphi rounds, the expert panel achieved consensus on the following top 5 items: (1) avoid routine use of antireflux medications for treatment of symptomatic gastroesophageal reflux disease or for treatment of apnea and desaturation in preterm infants, (2) avoid routine continuation of antibiotic therapy beyond 48 hours for initially asymptomatic infants without evidence of bacterial infection, (3) avoid routine use of pneumograms for predischarge assessment of ongoing and/or prolonged apnea of prematurity, (4) avoid routine daily chest radiographs without an indication for intubated infants, and (5) avoid routine screening term-equivalent or discharge brain MRIs in preterm infants.

conclusionsThe Choosing Wisely Top Five for newborn medicine highlights tests and treatments that cannot be adequately justified on the basis of efficacy, safety, or cost. This list serves as a starting point for quality improvement efforts to optimize both clinical outcomes and resource utilization in newborn care.

Indexed as

Health Care SurveysNeonatologyDelphi TechniqueHealth Services MisuseHumansPediatricsPractice Guidelines as TopicSocieties, MedicalUnited States

Identifiers

PMID26195536
PMCPMC9923615
OpenAlexW1948857070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.