Evidence map›Paper›PMID 26195297›Full record

ArticlePsychiatry research2015

Sex differences in abnormal white matter development associated with conduct disorder in children.

Jean Decety, Keith J Yoder, Benjamin B Lahey

Open access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. White matter correlates of psychopathic traits in a female community sample.Social cognitive and affective neuroscience · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jean DecetyChild Neurosuite - Department of Psychology, University of Chicago, Chicago, IL, United States; Department of Psychiatry and Behavioral Neuroscience, University of Chicago Medicine, Chicago, IL, United States. Electronic address: decety@uchicago.edu.
Keith J YoderChild Neurosuite - Department of Psychology, University of Chicago, Chicago, IL, United States.
Benjamin B LaheyDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago Medicine, Chicago, IL, United States; Department of Public Health Sciences, University of Chicago, Chicago, IL, United States.
University of Chicago · USChicago Department of Public Health · US

Funding

Neurological mechanisms in Emotional Processes of PsychopathyR01MH087525 · NIMH · UNIVERSITY OF CHICAGO · PI DECETY, JEAN · 2011 to 2014
$1.6M
Cognitive and Affective Neuroscience of Atypical Empathy in Conduct DisorderR01MH084934 · NIMH · UNIVERSITY OF CHICAGO · PI DECETY, JEAN · 2009 to 2012
$1.5M
NIMH NIH HHS R01 MH084934NIMH NIH HHS R01MH084934NIMH NIH HHS R01 MH087525
6 · The paper itself

Abstract

Associations between white matter pathway abnormalities and antisocial personality disorder in adults are well replicated, and there is some evidence for an association of white matter abnormalities with conduct disorder (CD) in adolescents. In this study, white matter maturation using diffusion tensor imaging (DTI) was examined in 110 children aged 10.0 ± 0.8 years selected to vary widely in their numbers of CD symptoms. The results replicated age-related increases in fractional anisotropy (FA) found in previous studies. There was not a significant association between the number of CD symptoms and FA, but CD symptoms were found to be significantly associated with greater axial and radial diffusivity in a broad range of white matter tracts, particularly in girls. In complementary analyses, there were similar significant differences in axial and radial diffusivity between children who met diagnostic criteria for CD and healthy children with no symptoms of CD, particularly in girls. Brain structural abnormalities may contribute to the emergence of CD in childhood, perhaps playing a greater role in girls.

Indexed as

AdolescentAdultBrainCase-Control StudiesChildChild, PreschoolConduct DisorderDiffusion Tensor ImagingFemaleHumansMaleReference ValuesSex FactorsWhite MatterConduct disorderDiffusion tensor imagingFractional anisotropyMRIWhite matter

Identifiers

PMID26195297
PMCPMC4536170
OpenAlexW1934077976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.