Evidence map›Paper›PMID 26195294›Full record

ArticlePsychiatry research2015

Assessing effects of prenatal alcohol exposure using group-wise sparse representation of fMRI data.

Jinglei Lv, Xi Jiang, Xiang Li, Dajiang Zhu, Shijie Zhao, Tuo Zhang, Xintao Hu, Junwei Han, Lei Guo, Zhihao Li and 3 more

Abstract readComparative Study
In one paragraph

Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Modeling task-based fMRI data via deep belief network with neural architecture search.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jinglei LvSchool of Automation, Northwestern Polytechnical University, Xi'an, China; Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Xi JiangCortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Xiang LiCortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Dajiang ZhuCortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Shijie ZhaoSchool of Automation, Northwestern Polytechnical University, Xi'an, China; Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Tuo ZhangSchool of Automation, Northwestern Polytechnical University, Xi'an, China; Cortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.
Xintao HuSchool of Automation, Northwestern Polytechnical University, Xi'an, China.
Junwei HanSchool of Automation, Northwestern Polytechnical University, Xi'an, China.
Lei GuoSchool of Automation, Northwestern Polytechnical University, Xi'an, China.
Zhihao LiBiomedical Imaging Technology Center, Emory University, 1760 Haygood Drive, Atlanta, GA, USA.
Claire ColesPsychiatry and Behavioral Sciences, Emory University, 1256 Briarcliff Road, Atlanta, GA, USA.
Xiaoping HuBiomedical Imaging Technology Center, Emory University, 1760 Haygood Drive, Atlanta, GA, USA.
Tianming LiuCortical Architecture Imaging and Discovery Lab, Department of Computer Science and Bioimaging Research Center, The University of Georgia, GSRC 415, Athens, GA, USA.

Funding

Assessing Large-scale Connectivities in Prenatal Cocaine Exposure Affected BrainsR01DA033393 · NIDA · UNIVERSITY OF GEORGIA · PI HU, XIAOPING P, LIU, TIANMING · 2012 to 2016
$1.6M
Assessing Large-scale Brain Connectivities in Mild Cognitive ImpairmentR01AG042599 · NIA · UNIVERSITY OF GEORGIA · PI LIU, TIANMING · 2013 to 2017
$1.4M
NIA NIH HHS R01 AG042599NIA NIH HHS R01AG-042599NIDA NIH HHS R01 DA033393NIDA NIH HHS R01DA-033393
6 · The paper itself

Abstract

Task-based fMRI activation mapping has been widely used in clinical neuroscience in order to assess different functional activity patterns in conditions such as prenatal alcohol exposure (PAE) affected brains and healthy controls. In this paper, we propose a novel, alternative approach of group-wise sparse representation of the fMRI data of multiple groups of subjects (healthy control, exposed non-dysmorphic PAE and exposed dysmorphic PAE) and assess the systematic functional activity differences among these three populations. Specifically, a common time series signal dictionary is learned from the aggregated fMRI signals of all three groups of subjects, and then the weight coefficient matrices (named statistical coefficient map (SCM)) associated with each common dictionary were statistically assessed for each group separately. Through inter-group comparisons based on the correspondence established by the common dictionary, our experimental results have demonstrated that the group-wise sparse coding strategy and the SCM can effectively reveal a collection of brain networks/regions that were affected by different levels of severity of PAE.

Indexed as

ArousalBrainBrain MappingCase-Control StudiesFemaleFetal Alcohol Spectrum DisordersHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleProblem SolvingReference ValuesYoung AdultGroup-wisePrenatal alcohol exposureSparse codingTask fMRI

Identifiers

PMID26195294
PMCPMC4536108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.