Evidence map›Paper›PMID 26195199›Full record

Trial reportCancer2015

Thyroid cancer patient perceptions of radioactive iodine treatment choice: Follow-up from a decision-aid randomized trial.

Anna M Sawka, Sharon Straus, Gary Rodin, Lineke Heus, James D Brierley, Richard W Tsang, Lorne Rotstein, Shereen Ezzat, Phillip Segal, Amiram Gafni and 2 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01083550 (Decision Aid on Radioactive Iodine Treatment for Early Stage Papillary Thyroid Cancer), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01083550 phase2 / phase3completednot on this map

Decision Aid on Radioactive Iodine Treatment for Early Stage Papillary Thyroid Cancer (Randomized Controlled Trial)

TypeinterventionalSponsorUniversity Health Network, TorontoRan2010 to 2016Enrolled74ConditionsThyroid CancerArmsDecision aid exposure
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Decision aids for people facing health treatment or screening decisions.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Patient-Perceived Lack of Choice in Receipt of Radioactive Iodine for Treatment of Differentiated Thyroid Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Anna M SawkaDivision of Endocrinology, Department of Medicine, University Health Network/University of Toronto, Toronto, Canada.
Sharon StrausDepartment of Medicine, St. Michael's Hospital/University of Toronto, Toronto, Canada.
Gary RodinDepartment of Psychosocial Oncology, University Health Network/University of Toronto, Toronto, Canada.
Lineke HeusDivision of Endocrinology, Department of Medicine, University Health Network/University of Toronto, Toronto, Canada.
James D BrierleyDepartment of Radiation Oncology, University Health Network/University of Toronto, Toronto, Canada.
Richard W TsangDepartment of Radiation Oncology, University Health Network/University of Toronto, Toronto, Canada.
Lorne RotsteinDepartment of Surgery, University Health Network/University of Toronto, Toronto, Canada.
Shereen EzzatDivision of Endocrinology, Department of Medicine, University Health Network/University of Toronto, Toronto, Canada.
Phillip SegalDivision of Endocrinology, Department of Medicine, University Health Network/University of Toronto, Toronto, Canada.
Amiram GafniDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada.
Kevin E ThorpeDalla Lana School of Public Health, University of Toronto/Keenan Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Canada.
David P GoldsteinDepartment of Otolaryngology and Head and Neck Surgery, University Health Network/University of Toronto, Toronto, Canada.
University of Toronto · CAMcMaster University · CASt. Michael's Hospital · CAUniversity Health Network · CA

Funding

Canadian Institutes of Health Research FRN 111416
6 · The paper itself

Abstract

backgroundPatient decision aids (P-DAs) inform medical decision making, but longer term effects are unknown. This article describes extended follow-up from a thyroid cancer treatment P-DA trial.

methodsIn this single-center, parallel-design randomized controlled trial conducted at a Canadian tertiary/quaternary care center, early-stage thyroid cancer patients from a P-DA trial were contacted 15 to 23 months after randomization/radioactive iodine (RAI) decision making to evaluate longer term outcomes. It was previously reported that the use of the computerized P-DA in thyroid cancer patients considering postsurgical RAI treatment significantly improved medical knowledge in comparison with usual care alone. The P-DA and control groups were compared for the following outcomes: feeling informed about the RAI treatment choice, decision satisfaction, decision regret, cancer-related worry, and physician trust. In a subgroup of 20 participants, in-depth interviews were conducted for a qualitative analysis.

resultsNinety-five percent (70 of 74) of the original population enrolled in follow-up at a mean of 17.1 months after randomization. P-DA users perceived themselves to be significantly more 1) informed about the treatment choice (P = .008), 2) aware of options (P = .009), 3) knowledgeable about treatment benefits (P = .020), and 4) knowledgeable about treatment risks/side effects (P = .001) in comparison with controls. There were no significant group differences in decision satisfaction (P = .142), decision regret (P = .199), cancer-related worry (P = .645), mood (P = .211), or physician trust (P = .764). In the qualitative analysis, the P-DA was perceived to have increased patient knowledge and confidence in decision making.

conclusionsThe P-DA improved cancer survivors' actual and long-term perceived medical knowledge with no adverse effects. More research on the long-term outcomes of P-DA use is needed.

Indexed as

AdultCanadaDecision Making, Computer-AssistedDecision Support TechniquesFemaleHealth Knowledge, Attitudes, PracticeHumansIodine RadioisotopesMaleMiddle AgedPatient ParticipationPatient SatisfactionRadiopharmaceuticalsRadiotherapyThyroid NeoplasmsIodine RadioisotopesRadiopharmaceuticalsdecision aidsdecision makingdecision support techniquesiodine radioisotopespatient satisfactionqualitative researchthyroid cancer

Identifiers

PMID26195199
PMCPMC4832354
OpenAlexW1570541650

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.