Evidence map›Paper›PMID 26195178›Full record

ArticleEuropean journal of pediatrics2016

Efficacy of colchicine in a child with relapsing bullous Henoch-Schönlein purpura.

Slimane Allali, Sylvie Fraitag, Benjamin Terrier, Christine Bodemer, Martin Chalumeau

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in European journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. IntravenousCase reports in pediatrics · 2020
    Article
  5. Article
  6. Colchicine: an ancient drug with novel applications.The British journal of dermatology · 2018
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Slimane AllaliDepartment of General Pediatrics, Hôpital Necker-Enfants Malades, APHP, Paris Descartes University, 149 rue de Sèvres, 75015, Paris, France. slimane.allali@nck.aphp.fr.
Sylvie FraitagDepartment of Pathology, Hôpital Necker-Enfants Malades, APHP, Paris Descartes University, 149 rue de Sèvres, 75015, Paris, France. sylvie.fraitag@nck.aphp.fr.
Benjamin TerrierDepartment of Internal Medicine, Hôpital Cochin, APHP, Paris Descartes University, 27 rue du Faubourg Saint-Jacques, 75014, Paris, France. benjamin.terrier@cch.aphp.fr.
Christine BodemerDepartment of Dermatology, Hôpital Necker-Enfants Malades, APHP, Paris Descartes University, 149 rue de Sèvres, 75015, Paris, France. christine.bodemer@nck.aphp.fr.
Martin ChalumeauDepartment of General Pediatrics, Hôpital Necker-Enfants Malades, APHP, Paris Descartes University, 149 rue de Sèvres, 75015, Paris, France. martin.chalumeau@nck.aphp.fr.
Université Paris Cité · FRDélégation Paris 5 · FRHôpital Necker-Enfants Malades · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledColchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. We report a case of pediatric HSP with severe chronic and relapsing cutaneous manifestations that were resistant to corticosteroids. Colchicine had remarkable therapeutic efficacy, with positive dechallenge and rechallenge, without any adverse effects.

conclusionColchicine should be considered for chronic, severe cutaneous lesions of pediatric HSP. WHAT IS KNOWN: Colchicine is not usually considered a treatment option for cutaneous lesions of Henoch-Schönlein purpura (HSP) in children. What is New: We report a case of pediatric HSP with severe cutaneous manifestations that responded well to colchicine. Colchicine should be considered for chronic cutaneous lesions of HSP in children.

Indexed as

Child, PreschoolChronic DiseaseColchicineHumansIgA VasculitisMaleRecurrenceColchicineChronic severe cutaneous lesionsColchicineHenoch-Schönlein purpuraImmunoglobulin A vasculitisLeukocytoclastic vasculitis

Identifiers

PMID26195178
OpenAlexW1757185621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.