ArticleBMC public health2015
Associations between residence at birth and mental health disorders: a spatial analysis of retrospective cohort data.
Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association between residence at birth and addiction service utilization: a spatial analysis of the Massachusetts birth record cohort.Frontiers in epidemiology · 2025Article
- Mapping the spatial disparities of HIV prevalence in Ethiopian zones using the generalized additive model.Scientific reports · 2024Article
- Environmental and Household-Based Spatial Risks for Tungiasis in an Endemic Area of Coastal Kenya.Tropical medicine and infectious disease · 2021Article
- Prenatal environmental exposures and associations with teen births.Journal of exposure science & environmental epidemiology · 2021Article
- Association of Adult Depression With Educational Attainment, Aspirations, and Expectations.Preventing chronic disease · 2020Article
- Examining the role of a retail density ordinance in reducing concentration of tobacco retailers.Spatial and spatio-temporal epidemiology · 2020Article
- Posttraumatic Stress Disorder in Maltreated Children Grown Up: The Influence of Neighborhood.Journal of traumatic stress · 2019Article
- Perceptions of Neighborhood Mediate the Relationship Between PTSD Symptoms and Coping in a Neighborhood-Matched Substance-Using Sample.Journal of addiction medicineArticle
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Authors and funding
5 authors.
Funding
Abstract
backgroundMental health disorders impact approximately one in four US adults. While their causes are likely multifactorial, prior research has linked the risk of certain mental health disorders to prenatal and early childhood environmental exposures, motivating a spatial analysis to determine whether risk varies by birth location.
methodsWe investigated the spatial associations between residence at birth and odds of depression, bipolar disorder, and post-traumatic stress disorder (PTSD) in a retrospective cohort (Cape Cod, Massachusetts, 1969-1983) using generalized additive models to simultaneously smooth location and adjust for confounders. Birth location served as a surrogate for prenatal exposure to the combination of social and environmental factors related to the development of mental illness. We predicted crude and adjusted odds ratios (aOR) for each outcome across the study area. The results were mapped to identify areas of increased risk.
resultsWe observed spatial variation in the crude odds ratios of depression that was still present even after accounting for spatial confounding due to geographic differences in the distribution of known risk factors (aOR range: 0.61-3.07, P = 0.03). Similar geographic patterns were seen for the crude odds of PTSD; however, these patterns were no longer present in the adjusted analysis (aOR range: 0.49-1.36, P = 0.79), with family history of mental illness most notably influencing the geographic patterns. Analyses of the odds of bipolar disorder did not show any meaningful spatial variation (aOR range: 0.58-1.17, P = 0.82).
conclusionSpatial associations exist between residence at birth and odds of PTSD and depression, but much of this variation can be explained by the geographic distributions of available risk factors. However, these risk factors did not account for all the variation observed with depression, suggesting that other social and environmental factors within our study area need further investigation.
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