Evidence map›Paper›PMID 26194744›Full record

ArticleJournal of assisted reproduction and genetics2015

Obesity adversely affects serum anti-müllerian hormone (AMH) levels in Caucasian women.

Vicky Moy, Sangita Jindal, Harry Lieman, Erkan Buyuk

Open access · bronzeAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  4. Early Life Body Fatness, Serum Anti-Müllerian Hormone, and Breast Density in Young Adult Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vicky MoyDepartment of Obstetrics, Gynecology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Block Building Room 630, Bronx, NY, 10461, USA.
Sangita JindalDepartment of Obstetrics, Gynecology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Block Building Room 630, Bronx, NY, 10461, USA.
Harry LiemanDepartment of Obstetrics, Gynecology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Block Building Room 630, Bronx, NY, 10461, USA.
Erkan BuyukDepartment of Obstetrics, Gynecology and Women's Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Block Building Room 630, Bronx, NY, 10461, USA. erbuyuk@yahoo.com.
Albert Einstein College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious studies regarding the effect of obesity on serum anti-müllerian hormone (AMH) levels have been conflicting. Our aim was to determine the effect of obesity on serum AMH levels among women from different racial backgrounds.

methodsThe medical records of 350 women (159 Caucasian, 99 African-American, 58 Hispanic, 34 Asian with ages 16-46) evaluated for infertility at an academic-affiliated center and who had AMH levels measured as part of their evaluation were reviewed. Age, AMH, body mass index (BMI), self-reported race, etiology of infertility, smoking history, maximum serum early follicular follicle-stimulating hormone (FSH) levels, antral follicle count (AFC), and history of ovarian surgery, chemotherapy, or radiotherapy were recorded.

resultsAge correlated negatively with AMH and antral follicle count across all races (p < 0.05). After adjusting for age, polycystic ovary syndrome diagnosis, and smoking, elevated BMI had a negative correlation with AMH in Caucasian women (β = 0.17, p = 0.01) but not in African-American, Hispanic, or Asian women.

conclusionElevated BMI correlates negatively with AMH in Caucasian women but not in African-American, Hispanic, or Asian women. Additional studies are needed to elucidate further the effect of race on the interaction between obesity and ovarian reserve.

Indexed as

AdolescentAdultAge FactorsAnti-Mullerian HormoneBiomarkersBody Mass IndexFemaleFollicle Stimulating HormoneFollow-Up StudiesHumansImmunoassayInfertilityMiddle AgedObesityPolycystic Ovary SyndromePregnancyAnti-Mullerian HormoneBiomarkersFollicle Stimulating HormoneAnti-müllerian hormone (AMH)Body mass indexObesityRace/ethnicity

Identifiers

PMID26194744
PMCPMC4595398
OpenAlexW1005681645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.