Evidence map›Paper›PMID 26194734›Full record

Observational studyJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2015

Relationship between Clinical and Polysomnography Measures Corrected for CPAP Use.

Erin M Kirkham, Susan R Heckbert, Edward M Weaver

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Obstructive sleep apnea illness perception relative to other common chronic conditions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  3. Observational
  4. Article
  5. Predicting CPAP Use and Treatment Outcomes Using Composite Indices of Sleep Apnea Severity.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erin M KirkhamDepartment of Otolaryngology/Head & Neck Surgery, University of Washington, Seattle, Washington.
Susan R HeckbertCardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle, WA.
Edward M WeaverDepartment of Otolaryngology/Head & Neck Surgery, University of Washington, Seattle, Washington.
University of Washington · US

Funding

Research Training in OtolaryngologyT32DC000018 · NIDCD · UNIVERSITY OF WASHINGTON · PI STONE, JENNIFER S. · 1989 to 2023
$7.8M
Nasal Turbinate Reduction & CPAP Outcomes for Sleep Apnea: A Sham-Controlled RCTR01HL084139 · NHLBI · UNIVERSITY OF WASHINGTON · PI WEAVER, EDWARD M · 2007 to 2011
$3.0M
Nasal Obstruction and Sleep Apnea Treatment OutcomesK23HL068849 · NHLBI · UNIVERSITY OF WASHINGTON · PI WEAVER, EDWARD M · 2003 to 2007
$764k
NHLBI NIH HHS K23 HL068849NHLBI NIH HHS R01 HL084139NIDCD NIH HHS T32 DC000018
6 · The paper itself

Abstract

objectivesThe changes in patient-reported measures of obstructive sleep apnea (OSA) burden are largely discordant with the change in apnea-hypopnea index (AHI) and other polysomnography measures before and after treatment. For patients treated with continuous positive airway pressure (CPAP), some investigators have theorized that this discordance is due in part to the variability in CPAP use. We aim to test the hypothesis that patient-reported outcomes of CPAP treatment have stronger correlations with AHI when it is corrected for mean nightly CPAP use.

methodsThis was a cross-sectional study of 459 adults treated with CPAP for OSA. Five patient-reported measures of OSA burden were collected at baseline and after 6 months of CPAP therapy. The correlations between the change in each patient-reported measure and the change in AHI as well as mean nightly AHI (corrected for CPAP use with a weighted average formula) were measured after 6 months of treatment. The same analysis was repeated for 4 additional polysomnography measures, including apnea index, arousal index, lowest oxyhemoglobin saturation, and desaturation index.

resultsThe change in AHI was weakly but significantly correlated with change in 2 of the 5 clinical measures. The change in mean nightly AHI demonstrated statistically significant correlations with 4 out of 5 clinical measures, though each with coefficients less than 0.3. Similar results were seen for apnea index, arousal index, lowest oxyhemoglobin saturation, and desaturation index.

conclusionsCorrection for CPAP use yielded overall small but significant improvements in the correlations between patient-reported measures of sleep apnea burden and polysomnography measures after 6 months of treatment.

Indexed as

Continuous Positive Airway PressureCross-Sectional StudiesFemaleHumansMaleMiddle AgedPolysomnographySeverity of Illness IndexSleep Apnea, ObstructiveTreatment Outcomeapnea-hypopnea indexCPAPoutcomequality of lifesleep apneasleepinesssymptom

Identifiers

PMID26194734
PMCPMC4623129
OpenAlexW1930189535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.