Trial reportSleep2015
Experimental Sleep Restriction Facilitates Pain and Electrically Induced Cortical Responses.
Trial report in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Effect of sleep loss on pain-New conceptual and mechanistic avenues.Frontiers in neuroscience · 2022Pooled it
- Article
- The Bidirectional Relationship Between Perioperative Sleep Deprivation and Postoperative Pain - Mechanisms and Clinical Implications: A Narrative Review.Journal of pain research · 2026Review
- Stress Management in Athletes: Predictive Effects of Sleep Deprivation-Induced Cognitive Control Changes on Competition Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Endogenous pain modulation after sleep restriction in migraine: a blinded crossover study.The journal of headache and pain · 2024Article
- Sleep-EEG in comorbid pain and insomnia: implications for the treatment of pain disorders.Pain reports · 2023Article
- Virtual reality hypnosis in the management of pain: Self-reported and neurophysiological measures in healthy subjects.European journal of pain (London, England) · 2023Article
- Experimental sleep restriction increases latency jitter in pain elicited cortical responses.Heliyon · 2021Article
- Effects of psychosocial work factors on number of pain sites: The role of sleep quality as mediator.BMC musculoskeletal disorders · 2019Article
- A prospective study of work-private life conflict and number of pain sites: moderated mediation by sleep problems and support.Journal of behavioral medicine · 2019Article
- Sleep duration mediates abdominal and lower-extremity pain after night work in nurses.International archives of occupational and environmental health · 2019Article
- Pain, pain intensity and pain disability in high school students are differently associated with physical activity, screening hours and sleep.BMC musculoskeletal disorders · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesSleep restriction (SR) has been hypothesized to sensitize the pain system. The current study determined whether experimental sleep restriction had an effect on experimentally induced pain and pain-elicited electroencephalographic (EEG) responses.
designA paired crossover study.
interventionPain testing was performed after 2 nights of 50% SR and after 2 nights with habitual sleep (HS).
settingLaboratory experiment at research center.
participantsSelf-reported healthy volunteers (n = 21, age range: 18-31 y). MEASUREMENTS AND
resultsBrief high-density electrical stimuli to the forearm skin produced pinprick-like pain. Subjective pain ratings increased after SR, but only in response to the highest stimulus intensity (P = 0.018). SR increased the magnitude of the pain-elicited EEG response analyzed in the time-frequency domain (P = 0.021). Habituation across blocks did not differ between HS and SR. Event-related desynchronization (ERD) was reduced after SR (P = 0.039). Pressure pain threshold of the trapezius muscle region also decreased after SR (P = 0.017).
conclusionSleep restriction (SR) increased the sensitivity to pressure pain and to electrically induced pain of moderate, but not low, intensity. The increased electrical pain could not be explained by a difference in habituation. Increased response magnitude is possibly related to reduced processing within the somatosensory cortex after partial SR.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.