Trial reportSleep2015
Benefits of Sleep Extension on Sustained Attention and Sleep Pressure Before and During Total Sleep Deprivation and Recovery.
Trial report in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02820649 (Protective Effects of Exercise Training on Endothelial Dysfunction Induced by Total Sleep Deprivation in Healthy Subjects), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Protective Effects of Exercise Training on Endothelial Dysfunction Induced by Total Sleep Deprivation in Healthy Subjects
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- Sleep Management and Performance in Offshore Sailing Regattas: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Effects of Sleepwear Incorporating a DPV576 Functional Polyester Fabric on Wearable ECG-Derived Sleep Consolidation: A Randomized Two-Period Crossover Study Under Free-Living Conditions.Sensors (Basel, Switzerland) · 2026Trial
- Both acute and chronic caffeine consumption affect cardiovascular responses to total sleep deprivation.Frontiers in cardiovascular medicine · 2026Trial
- Caffeine Intake Alters Recovery Sleep after Sleep Deprivation.Nutrients · 2024Trial
- Relationship between Habitual Caffeine Consumption, Attentional Performance, and Individual Alpha Frequency during Total Sleep Deprivation.International journal of environmental research and public health · 2023Trial
- Six nights of sleep extension increases regional cerebral oxygenation without modifying cognitive performance at rest or following acute aerobic exercise.Journal of sleep research · 2022Trial
- Effect of five nights of sleep extension on peripheral vascular function: a randomized crossover investigation into long sleep duration.Sleep medicine · 2022Trial
- Trial
- Sleepiness, sleep deprivation, quality of life, mental symptoms and perception of academic environment in medical students.BMC medical education · 2021Trial
- Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target.British journal of clinical pharmacology · 2019Trial
- Sleep disturbances after an ultra-trail endurance race: a field study.Sleep medicine: X · 2026Article
- Insomnia and Its Therapeutic Approaches Among University Students in Madrid.Current therapeutic research, clinical and experimental · 2026Article
- The Role of Sleep Banking in Reducing Cognitive and Motor Impairments from Subsequent Sleep Restriction: A Narrative Review.Clocks & sleep · 2026Review
- Relations between sleep quality and academic performance among Vietnamese high-school students.Frontiers in psychology · 2026Article
- Can sleep be "banked"? A PRO-CON debate.Sleep · 2025Article
- Effects of a 24/48 to 48/96 Shift Schedule Change on Firefighter Sleep and Health: Short-Term Improvements and Six-Month Stability.International journal of environmental research and public health · 2025Article
- Combined effects of moderate normobaric hypoxia and sleep restriction on visual and auditory integration.Scientific reports · 2025Article
- Cognitive benefits of sleep: a narrative review to explore the relevance of glucose regulation.Sleep advances : a journal of the Sleep Research Society · 2025Review
- Chronotype, cognitive outcomes, and neural dynamics: recent evidence and potential mechanisms with implications for perioperative period.Frontiers in neuroscience · 2025Review
- The Effect of Acute Sleep Extension on Blood Pressure Is Dependent on the Change in Sleep Efficiency.Clocks & sleep · 2024Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effects of 6 nights of sleep extension on sustained attention and sleep pressure before and during total sleep deprivation and after a subsequent recovery sleep.
designSubjects participated in two experimental conditions (randomized cross-over design): extended sleep (EXT, 9.8 ± 0.1 h (mean ± SE) time in bed) and habitual sleep (HAB, 8.2 ± 0.1 h time in bed). In each condition, subjects performed two consecutive phases: (1) 6 nights of either EXT or HAB (2) three days in-laboratory: baseline, total sleep deprivation and after 10 h of recovery sleep.
settingResidential sleep extension and sleep performance laboratory (continuous polysomnographic recording).
participants14 healthy men (age range: 26-37 years).
interventionsEXT vs. HAB sleep durations prior to total sleep deprivation. MEASUREMENTS AND
resultsTotal sleep time and duration of all sleep stages during the 6 nights were significantly higher in EXT than HAB. EXT improved psychomotor vigilance task performance (PVT, both fewer lapses and faster speed) and reduced sleep pressure as evidenced by longer multiple sleep latencies (MSLT) at baseline compared to HAB. EXT limited PVT lapses and the number of involuntary microsleeps during total sleep deprivation. Differences in PVT lapses and speed and MSLT at baseline were maintained after one night of recovery sleep.
conclusionSix nights of extended sleep improve sustained attention and reduce sleep pressure. Sleep extension also protects against psychomotor vigilance task lapses and microsleep degradation during total sleep deprivation. These beneficial effects persist after one night of recovery sleep.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.