ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2016
Vitamin D deficiency in adult fracture patients: prevalence and risk factors.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- The Effect of Bolus Vitamin DJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Trial
- Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation.Journal of orthopaedic translation · 2026Review
- Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations.Journal of bone and mineral metabolism · 2025Article
- Vitamin D Levels During Fracture Healing in Children.Physiological research · 2024Article
- Prevalence and Associated Factors of Vitamin D Deficiency in High Altitude Region in Saudi Arabia: Three-Year Retrospective Study.International journal of general medicine · 2023Article
- The Effect of Vitamin D Supplementation for Bone Healing in Fracture Patients: A Systematic Review.Advances in orthopedics · 2023Review
- Serum sclerostin levels in osteoporotic fracture patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Association between Vitamin D and Cognitive Deficiency in Alcohol Dependence.Healthcare (Basel, Switzerland) · 2022Article
- Vitamin D status and vitamin D deficiency risk factors among pregnancy of Shanghai in China.BMC pregnancy and childbirth · 2021Article
- Evaluation of Serum 25-Hydroxyvitamin DOrthopaedic surgery · 2021Article
- Possible Roles of Vitamin D in Bone Grafting.Cureus · 2021Review
- Sub-optimal serum 25-hydroxyvitamin D level affects 2-year survival after hip fracture surgery.Journal of bone and mineral metabolism · 2020Article
- Association Between Serum 25-Hydroxyvitamin D Concentrations and Chronic Pain: Effects of Drinking Habits.Journal of pain research · 2020Article
- Therapeutic approaches to osteosarcopenia: insights for the clinician.Therapeutic advances in musculoskeletal disease · 2019Review
- Prevalence of vitamin D deficiency in orthopaedic patients - A single centre study.Journal of clinical orthopaedics and traumaArticle
- Infected nonunion of tibia.Indian journal of orthopaedicsArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAlthough vitamin D levels are not routinely monitored in outpatient fracture patients, identification of fracture patients with a deficient vitamin D status may be clinically relevant because of the potential role of vitamin D in fracture healing. This study aimed to determine the prevalence of and risk factors for vitamin D deficiency in non-operatively treated adult fracture patients. PATIENTS AND
methodsVitamin D levels were determined in a cross-sectional study of adult patients, who were treated non-operatively for a fracture of the upper or lower extremity in the outpatient clinic of a level 1 trauma center, during one calendar year. Potential risk factors for (severe) vitamin D deficiency were analyzed using multivariable logistic regression analysis.
resultsA total of 208 men and 319 women with a mean age of 49.7 years (SD 19.9) were included. In this population, 71 % had a serum calcidiol <75 nmol/L, 40 % were vitamin D deficient (serum calcidiol <50 nmol/L) and 11 % were severely vitamin D deficient (serum calcidiol <25 nmol/L). Smoking and season (winter and spring) were independent risk factors for vitamin D deficiency. An increasing age, a non-Caucasian skin type, winter and smoking were identified as independent risk factors for severe vitamin D deficiency. The use of vitamin D, alcohol consumption and higher average daily sun exposure were independent protective factors against (severe) vitamin D deficiency.
conclusionGiven the potential role of vitamin D in fracture healing, clinicians treating adult fracture patients should be aware of the frequent presence of vitamin D deficiency during the winter, especially in smoking and non-Caucasian patients. Research on the effect of vitamin D deficiency or supplementation on fracture healing is needed, before suggesting routine monitoring or supplementation.
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