Evidence map›Paper›PMID 26194426›Full record

ArticleAIDS and behavior2016

Antiretroviral Treatment and Sexual Risk Behavior in South Africa.

Kathryn Risher, Thomas Rehle, Leickness Simbayi, Olive Shisana, David D Celentano

Abstract read
In one paragraph

Article in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Population prevalence of sexually transmitted infections in a high HIV burden district in KwaZulu-Natal, South Africa: Implications for HIV epidemic control.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kathryn RisherDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St, W6604, Baltimore, MD, 20205, USA. krisher1@jhu.edu.
Thomas RehleHuman Sciences Research Council, Cape Town, South Africa.
Leickness SimbayiHuman Sciences Research Council, Cape Town, South Africa.
Olive ShisanaHuman Sciences Research Council, Cape Town, South Africa.
David D CelentanoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St, W6604, Baltimore, MD, 20205, USA.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
NIAID NIH HHS 1P30AI094189NIAID NIH HHS P30 AI094189NIAID NIH HHS T32 AI102623NIAID NIH HHS T32AI102623PEPFARPHS HHS 3U2GGH000570
6 · The paper itself

Abstract

The sexual behavior of individuals living with HIV determines the onward transmission of HIV. With the understanding that antiretroviral therapy (ART) prevents transmission of HIV, the sexual behaviors of the individuals not on ART with unsuppressed viral loads becomes of the greatest importance in elucidating transmission. We assessed the association between being on ART and sexual risk behavior among those living with HIV in a nationally representative population-based cross-sectional survey of households in South Africa that was conducted in 2012. Of 2237 adults (aged 15-49) who tested HIV-seropositive, 667 (29.8 %) had detectable antiretroviral drugs in their blood specimens. Among males, 77.7 % of those on ART reported having had sex in the past year contrasted with 88.4 % of those not on ART (p = 0.001); among females, 72.2 % of those on ART reported having had sex in the past year while 80.3 % of those not on ART did (p < 0.001). For males and females, the odds of reporting consistent condom use and condom use at last sex were statistically significantly higher for individuals on ART compared to those not on ART (males: consistent condom use aOR 2.8, 95 % CI 1.6-4.9, condom use at last sex aOR 2.6, 95 % CI 1.5-4.6; females: consistent condom use aOR 2.3, 95 % CI 1.7-3.1, condom use at last sex aOR 2.3, 95 % CI 1.7-3.1), while there were no statistically significant differences in odds of reporting multiple sexual partners in the past year. In this nationally representative population-based survey of South African adults, we found evidence of less risky sexual risk behavior among people living with HIV on ART compared to those not on ART.

Indexed as

Antiretroviral Therapy, Highly ActiveRisk-TakingSexual BehaviorAdolescentAdultCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMiddle AgedPopulation SurveillanceRiskSouth AfricaSurveys and QuestionnairesViral LoadAntiretroviral therapyPeople living with HIVSexual behaviorSouth Africa

Identifiers

PMID26194426
PMCPMC4721939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.