ArticleCancer research and treatment2016
Second Primary Cancer after Diagnosis and Treatment of Cervical Cancer.
Article in Cancer research and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The risk for subsequent primary lung cancer after cervical carcinoma: A quantitative analysis based on 864,627 cases.PloS one · 2024Pooled it
- Increased risk of second cancers at sites associated with HPV after a prior HPV-associated malignancy, a systematic review and meta-analysis.British journal of cancer · 2019Pooled it
- Second primary cancers among females with a first primary cervical, uterine and ovarian cancer: a population-based study in North Portugal.Cancer causes & control : CCC · 2026Article
- The Anticancer Journey of Liquiritin: Insights into Its Mechanisms and Therapeutic Prospects.Current medicinal chemistry · 2025Review
- Association between radiation therapy for primary endometrial cancer and risk of second primary malignancies: a retrospective cohort study.Scientific reports · 2024Article
- Differences of characteristics, influencing factors, and treatment effects on the survival in patients with first and second primary cervical cancer.Preventive medicine reports · 2023Article
- Nomograms constructed for predicting diagnosis and prognosis in cervical cancer patients with second primary malignancies: a SEER database analysis.Journal of cancer research and clinical oncology · 2023Article
- Second Malignancies Following Primary Cervical Cancer Diagnosis: Analysis of the SEER Database.Cureus · 2022Article
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- Ultrasound-Targeted Microbubble Destruction Enhances the Inhibitive Efficacy of miR-21 Silencing in HeLa Cells.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Survival analysis of second primary malignancies after cervical cancer using a competing risk model: implications for prevention and surveillance.Annals of translational medicine · 2021Article
- Conditional relative survival of cervical cancer: a Korean National Cancer Registry Study.Journal of gynecologic oncology · 2021Article
- Leiomyosarcoma of the Rectum as a Radiation-Induced Second Malignancy after Cervical Cancer Treatment: Case Report with Review of the Literature.Case reports in oncological medicine · 2019Article
- Incidences and risk factors of metachronous vulvar, vaginal, and anal cancers after cervical cancer diagnosis.Gynecologic oncology · 2018Article
- Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.Oncotarget · 2018Article
- Activation of IL-8 and its participation in cancer in schizophrenia patients: new evidence for the autoimmune hypothesis of schizophrenia.Neuropsychiatric disease and treatment · 2018Article
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- Health Behaviors and Associated Sociodemographic Factors in Cervical Cancer Survivors Compared with Matched Non-Cancer Controls.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was conducted to investigate the incidence and survival outcomes of second primary cancers after the diagnosis of cervical cancer. MATERIALS AND
methodsData from the Korea Central Cancer Registry between 1993 and 2010 were reviewed and analyzed. Standardized incidence ratios (SIRs) of second primary cancers among women with cervical cancer were analyzed. Kaplan-Meier survival curves were constructed for cervical cancer patients with or without a second primary cancer.
resultsAmong 72,805 women with cervical cancer, 2,678 (3.68%) developed a second primary cancer within a mean follow-up period of 7.34 years. The overall SIR for a second cancer was 1.08 (95% confidence interval, 1.04 to 1.12). The most frequent sites of second primary cancers were the vagina, bone and joints, vulva, anus, bladder, lung and bronchus, corpus uteri, and esophagus. However, the incidence rates of four second primary cancers (breast, rectum, liver, and brain) were decreased. The 5-year and 10-year overall survival rates were 78.3% and 72.7% in all women with cervical cancer, and for women with a second primary cancer, these rates were 83.2% and 65.5% from the onset of cervical cancer and 54.9% and 46.7% from the onset of the second primary cancer, respectively.
conclusionThe incidence rates of second primary cancers were increased in women with cervical cancer compared to the general population, with the exception of four decreasing cancers. The 10-year overall survival rates were decreased in cervical cancer patients with a second primary cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.