ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2015
Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2.
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Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 1 of them a synthesis that pooled it.
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109citing papers in PubMed, 1 pooled it
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Who cites it
109 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Role of Imaging Genetics in Alzheimer's Disease: A Systematic Review and Current Update.CNS & neurological disorders drug targets · 2024Pooled it
- Pilot study of repeated blood-brain barrier disruption in patients with mild Alzheimer's disease with an implantable ultrasound device.Alzheimer's research & therapy · 2022Trial
- A longitudinal analysis of T1-weighted MRI features associated with progression from mild cognitive impairment to Alzheimer's disease.BMC medical imaging · 2026Article
- CSF microtubule-associated protein 1 light chain 3A and 3B levels are associated with tau pathology and Alzheimer's disease risk through amyloid deposition and microglial signaling.Journal of neuroinflammation · 2026Article
- Staging Alzheimer's disease through amyloid and tau PET.Brain : a journal of neurology · 2026Article
- μ Opioid Modulation of Sensorimotor Functional Connectivity in Autism: Insights From a Pharmacological Neuroimaging Investigation Using Tianeptine.Biological psychiatry global open science · 2026Article
- Association of hippocampus, entorhinal cortex, and amygdala with thyroid function: a bilateral volumetric analysis.Thyroid research · 2026Article
- Neural and Behavioral Predictors of Speech Motor Sequence Learning in Primary Progressive Aphasia.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Alzheimer's disease polygenic risk score associates with hippocampal subfield atrophy and immune-related genetic mechanism.Frontiers in aging neuroscience · 2026Article
- Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic.Frontiers in aging neuroscience · 2026Article
- Hippocampal volume moderates the association between cerebrospinal fluid growth-associated protein 43 and episodic memory performance in older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2025Article
- Multi-Modal Deep Clustering Survival Machines for Alzheimer's Disease Subtype Discovery.... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision · 2025Article
- The longitudinal effects of global and regional brain measurements on cognitive abilities.Scientific reports · 2025Article
- Harmonization of Structural Brain Connectivity Through Distribution Matching.Human brain mapping · 2025Article
- Harmonization of Structural Brain Connectivity through Distribution Matching.bioRxiv : the preprint server for biology · 2025Article
- Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer's disease: a neuropsychological data-driven approach.Alzheimer's research & therapy · 2025Article
- Reconstructing physiological signals from fMRI across the adult lifespan.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Revealing excitation-inhibition imbalance in Alzheimer's disease using multiscale neural model inversion of resting-state functional MRI.Communications medicine · 2025Article
- Optimizing ultra-rapid compressed-sensing MPRAGE acquisitions for brain morphometry.Frontiers in neuroimaging · 2025Article
- Article
49 more citing papers are in PubMed but not listed here.
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Authors and funding
43 authors.
Clifford R JackDepartment of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address: jack.clifford@mayo.edu.
Josephine BarnesDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK.
Matt A BernsteinDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Bret J BorowskiDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
James BrewerDepartment of Neuroscience, University of California at San Diego, La Jolla, CA, USA.
Shona CleggDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK.
Anders M DaleDepartment of Neuroscience, University of California at San Diego, La Jolla, CA, USA.
Owen CarmichaelDepartment of Neurology, University of California at Davis, Davis, CA, USA.
Christopher ChingDepartment of Neurology, Imaging Genetics Center, Institute for Neuroimaging & Informatics, University of Southern California, Marina del Rey, CA, USA.
Charles DeCarliDepartment of Neurology, University of California at Davis, Davis, CA, USA; Center for Neuroscience, University of California at Davis, Davis, CA, USA.
Rahul S DesikanDepartment of Radiology, University of California at San Diego, La Jolla, CA, USA.
Christine Fennema-NotestineDepartment of Radiology, University of California at San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California at San Diego, La Jolla, CA, USA.
Anders M FjellDepartment of Psychology, University of Oslo, Oslo, Norway.
Evan FletcherDepartment of Neurology, University of California at Davis, Davis, CA, USA; Center for Neuroscience, University of California at Davis, Davis, CA, USA.
Nick C FoxDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK.
Jeff GunterDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Boris A GutmanDepartment of Neurology, Imaging Genetics Center, Institute for Neuroimaging & Informatics, University of Southern California, Marina del Rey, CA, USA.
Dominic HollandDepartment of Neuroscience, University of California at San Diego, La Jolla, CA, USA.
Xue HuaDepartment of Neurology, Imaging Genetics Center, Institute for Neuroimaging & Informatics, University of Southern California, Marina del Rey, CA, USA.
Philip InselDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Kejal KantarciDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ron J KillianyDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, USA.
Gunnar KruegerSiemens Medical Solutions, Boston, MA, USA.
Kelvin K LeungTranslational Imaging Group, Centre for Medical Image Computing, University College London, London, United Kingdom.
Scott MackinDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA.
Pauline MaillardDepartment of Neurology, University of California at Davis, Davis, CA, USA; Center for Neuroscience, University of California at Davis, Davis, CA, USA.
Ian B MaloneDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK.
Niklas MattssonClinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, University of Gothenburg, Mölndal, Sweden.
Linda McEvoyDepartment of Radiology, University of California at San Diego, La Jolla, CA, USA.
Marc ModatDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK; Translational Imaging Group, Centre for Medical Image Computing, University College London, London, United Kingdom.
Susanne MuellerDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Radiology, University of California at San Francisco, San Francisco, CA, USA.
Rachel NoshenyDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Radiology, University of California at San Francisco, San Francisco, CA, USA.
Sebastien OurselinDepartment of Neurodegenerative Disease, Dementia Research Centre, Institute of Neurology, University College London, London, UK; Translational Imaging Group, Centre for Medical Image Computing, University College London, London, United Kingdom.
Norbert SchuffDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Radiology, University of California at San Francisco, San Francisco, CA, USA.
Matthew L SenjemDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Alix SimonsonDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA.
Paul M ThompsonDepartment of Neurology, Imaging Genetics Center, Institute for Neuroimaging & Informatics, University of Southern California, Marina del Rey, CA, USA.
Dan RettmannMR Applications and Workflow, GE Healthcare, Rochester, MN, USA.
Prashanthi VemuriDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Kristine WalhovdDepartment of Psychology, University of Oslo, Oslo, Norway.
Yansong ZhaoPhilips Healthcare, Cleveland, OH, USA.
Samantha ZukDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Michael WeinerDepartment of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA; Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA; Department of Radiology, University of California at San Francisco, San Francisco, CA, USA; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; Department of Neurology, University of California at San Francisco, San Francisco, CA, USA.
Funding
Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0MTR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1MPREDICTING ALZHEIMERS DISEASE WITH MAGNETIC RESONANCER01AG011378 · NIA · MAYO CLINIC ROCHESTER · PI JACK, CLIFFORD R. · 1993 to 2017
$12.1MCharacterizing Cognitive Decline in Late Life Depression: The ADNI-D ProjectR01MH098062 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Robert Scott Mackin · 2013 to 2026
$9.1MValidating the New Criteria for Preclinical Alzheimer's diseaseR01AG041851 · NIA · MAYO CLINIC ROCHESTER · PI JACK, CLIFFORD R., KNOPMAN, DAVID S · 2012 to 2021
$6.3MAlzheimer's disease risk analyzed using population imaging genomicsR01AG040060 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2011 to 2016
$2.5MNIA NIH HHS R01 AG011378NIA NIH HHS R01 AG040060NIA NIH HHS R01 AG041851NIA NIH HHS U01 AG024904NIBIB NIH HHS P41 EB015922NIMH NIH HHS R01 MH098062
Abstract
introductionAlzheimer's Disease Neuroimaging Initiative (ADNI) is now in its 10th year. The primary objective of the magnetic resonance imaging (MRI) core of ADNI has been to improve methods for clinical trials in Alzheimer's disease (AD) and related disorders.
methodsWe review the contributions of the MRI core from present and past cycles of ADNI (ADNI-1, -Grand Opportunity and -2). We also review plans for the future-ADNI-3.
resultsContributions of the MRI core include creating standardized acquisition protocols and quality control methods; examining the effect of technical features of image acquisition and analysis on outcome metrics; deriving sample size estimates for future trials based on those outcomes; and piloting the potential utility of MR perfusion, diffusion, and functional connectivity measures in multicenter clinical trials. DISCUSSION: Over the past decade the MRI core of ADNI has fulfilled its mandate of improving methods for clinical trials in AD and will continue to do so in the future.
Indexed as
Magnetic Resonance ImagingAlzheimer DiseaseBiomarkersBrainCognition DisordersHistory, 20th CenturyHistory, 21st CenturyHumansImage Processing, Computer-AssistedPositron-Emission TomographySpin LabelsBiomarkersSpin LabelsADNIAlzheimer's diseaseAlzheimer's Disease Neuroimaging InitiativeDiffusionMRINeuroimagingPerfusionResting functional MRI
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