ArticleIntensive care medicine2015
Consensus statement from the 2014 International Microdialysis Forum.
Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 173 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multimodality Monitoring Directed Management of Patients Suffering From Traumatic Brain Injury
Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.
Who cites it
173 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effects of lactate-based therapies on intracranial pressure and brain metabolism of patients with acute brain injury: a systematic review.Critical care (London, England) · 2026Pooled it
- Cerebral blood flow, autoregulation and vascular reactivity in normal pressure hydrocephalus: a systematic review.Fluids and barriers of the CNS · 2025Pooled it
- Red blood cell transfusion strategy in traumatic brain injury patients: a systematic review and meta-analysis.European journal of medical research · 2025Pooled it
- The Impact of Short-Term Hyperoxia on Cerebral Metabolism: A Systematic Review and Meta-Analysis.Neurocritical care · 2022Pooled it
- A systematic review of cerebral microdialysis and outcomes in TBI: relationships to patient functional outcome, neurophysiologic measures, and tissue outcome.Acta neurochirurgica · 2017Pooled it
- A randomized, double-blind trial comparing the effect of two blood pressure targets on global brain metabolism after out-of-hospital cardiac arrest.Critical care (London, England) · 2023Trial
- Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Trial
- Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury.Journal of neuroinflammation · 2021Trial
- Bedside microdialysis for detection of early brain injury after out-of-hospital cardiac arrest.Scientific reports · 2021Trial
- Double hemispheric Microdialysis study in poor-grade SAH patients.Scientific reports · 2020Trial
- Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury.Critical care (London, England) · 2018Trial
- Advances in imaging studies of contusion penumbra.IBRO neuroscience reports · 2026Review
- Intracerebral Glutamate and Glycerol in Severe Acute Brain Injury: Retrospective Study of Association With Neuroworsening and Outcome.Acta anaesthesiologica Scandinavica · 2026Observational
- Subcutaneous glucose tracking during extreme perioperative perfusion stress: a prospective microdialysis study.Journal of clinical monitoring and computing · 2026Article
- Cerebral Vasospasm After Traumatic Subarachnoid Hemorrhage: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Management and outcome of patients with traumatic brain injury treated in three major Nordic intensive care units: a comparative cohort study.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Observational
- Cerebral glycerol during haemorrhagic shock in normal and raised intracranial pressure resuscitated with total REBOA: an experimental porcine study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Glucose and Lactate Concentrations in Plasma, Cerebrospinal Fluid, and Brain Parenchyma Following Aneurysmal Subarachnoid Hemorrhage: A Cross-compartmental Correlation Study.Neurocritical care · 2026Article
- microGLYMPH: a conceptual translational roadmap for microdialysis‑based assessment of CSF-interstitial solute exchange in acquired brain injury.Critical care (London, England) · 2026Review
- Dose-dependent cerebral metabolic impairment in a swine model of carbon monoxide poisoning.Neurotoxicology · 2026Article
113 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
48 authors.
Funding
Abstract
Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical application of cerebral microdialysis was published. Since then, there have been significant advances in the clinical use of microdialysis in neurocritical care. The objective of this review is to report on the International Microdialysis Forum held in Cambridge, UK, in April 2014 and to produce a revised and updated consensus statement about its clinical use including technique, data interpretation, relationship with outcome, role in guiding therapy in neurocritical care and research applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.