Trial reportPloS one2015
Effects of Computer-Aided Interlimb Force Coupling Training on Paretic Hand and Arm Motor Control following Chronic Stroke: A Randomized Controlled Trial.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Computer-aided Interlimb Force Coupling Training on Paretic Hand and Arm Motor Control Following Chronic Stroke
A Study on Visual Feedback Motor Control Training Using Near-Infrared Spectroscopy (fNIRS) Brain Functional Imaging for Walking Function Recovery in Stroke Patients
Who cites it
17 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Comparative effectiveness of non-pharmacological interventions for post-stroke upper limb motor dysfunction: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in aging neuroscience · 2026Pooled it
- Effect of different modalities of artificial intelligence rehabilitation techniques on patients with upper limb dysfunction after stroke-A network meta-analysis of randomized controlled trials.Frontiers in neurology · 2023Pooled it
- Effectiveness and Success Factors of Bilateral Arm Training After Stroke: A Systematic Review and Meta-Analysis.Frontiers in aging neuroscience · 2022Pooled it
- Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020Pooled it
- Comparison of bilateral and unilateral upper limb training in people with stroke: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Pooled it
- Virtual reality for stroke rehabilitation.The Cochrane database of systematic reviews · 2017Pooled it
- Comparative Efficacy of Exercise Modalities for Motor Function Recovery After Acute Ischemic Stroke: A Systematic Review and Bayesian Network Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- Post-Stroke Rehabilitation: Neurophysiology Processes of Bilateral Movement Training and Interlimb Coupling-A Systematic Review.Journal of clinical medicine · 2025Review
- Grip force release is impaired in parkinson's disease during a force tracking task.Experimental brain research · 2024Article
- Robot-assisted therapy in stratified intervention: a randomized controlled trial on poststroke motor recovery.Frontiers in neurology · 2024Article
- Influencing factors of corticomuscular coherence in stroke patients.Frontiers in human neuroscience · 2024Review
- A biomedical decision support system for meta-analysis of bilateral upper-limb training in stroke patients with hemiplegia.Open life sciences · 2023Article
- A rehabilitative approach beyond the acute stroke event: a scoping review about functional recovery perspectives in the chronic hemiplegic patient.Frontiers in neurology · 2023Article
- Bilateral Tactile Feedback-Enabled Training for Stroke Survivors Using Microsoft KinectSensors (Basel, Switzerland) · 2019Article
- Bimanual coordination deficits in hands following stroke and their relationship with motor and functional performance.Journal of neuroengineering and rehabilitation · 2019Article
- Upper limb strength training in subacute stroke patients: study protocol of a randomised controlled trial.Trials · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe investigated the training effects of interlimb force coupling training on paretic upper extremity outcomes in patients with chronic stroke and analyzed the relationship between motor recovery of the paretic hand, arm and functional performances on paretic upper limb.
designA randomized controlled trial with outcome assessment at baseline and after 4 weeks of intervention.
settingTaipei Veterans General Hospital, National Yang-Ming University.
participantsThirty-three subjects with chronic stroke were recruited and randomly assigned to training (n = 16) and control groups (n = 17).
interventionsThe computer-aided interlimb force coupling training task with visual feedback included different grip force generation methods on both hands.
main outcome measuresThe Barthel Index (BI), the upper extremity motor control Fugl-Meyer Assessment (FMA-UE), the Motor Assessment Score (MAS), and the Wolf Motor Function Test (WMFT). All assessments were executed by a blinded evaluator, and data management and statistical analysis were also conducted by a blinded researcher.
resultsThe training group demonstrated greater improvement on the FMA-UE (p<.001), WMFT (p<.001), MAS (p = .004) and BI (p = .037) than the control group after 4 weeks of intervention. In addition, a moderate correlation was found between the improvement of scores for hand scales of the FMA and other portions of the FMA UE (r = .528, p = .018) or MAS (r = .596, p = .015) in the training group.
conclusionComputer-aided interlimb force coupling training improves the motor recovery of a paretic hand, and facilitates motor control and enhances functional performance in the paretic upper extremity of people with chronic stroke.
trial registrationClinicalTrials.gov NCT02247674.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.