ArticlePloS one2015
Short- and Long-Term Outcomes in Very Low Birth Weight Infants with Admission Hypothermia.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- The Effect of High and Low Ambient Temperature on Infant Health: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Interventions to prevent hypothermia at birth in preterm and/or low birth weight infants.The Cochrane database of systematic reviews · 2018Pooled it
- Early postnatal hypothermia in critically transported newborns at a Chinese tertiary care neonatal centre: a retrospective study.BMJ paediatrics open · 2026Observational
- A regional quality-improvement collaborative to reduce early neonatal hypothermia in critically ill newborns.Translational pediatrics · 2026Article
- Neonatal intensive care unit discharge education interventions and their effects on maternal sensitivity and neurocognitive development of premature infants: a protocol for a systematic review.Systematic reviews · 2025Article
- Temperature and Humidity During Different Neonatal Respiratory Support Modes: An In-Vitro Performance of Four Heated Humidifiers.Pediatric pulmonology · 2025Article
- Delayed admission temperature normalisation in preterm infants <32 weeks: impact on mortality and neonatal morbidities.BMJ paediatrics open · 2025Article
- Association between maternal khat use and other determinants and low birth weight in Halaba Zone, South Ethiopia: an unmatched case-control study.Frontiers in pediatrics · 2025Article
- Compliance with the Golden Hour bundle in deliveries attended by a specialized neonatal transport team compared with staff at non-tertiary centres.Paediatrics & child health · 2024Article
- Hypothermia in preterm infants admitted to low-resource neonatal units in northern Nigeria: an observational study of occurrence and risk factors.BMC pediatrics · 2024Observational
- Prevalence and determinant factors of low birth weight in Marrakesh province, Morocco: cross sectorial survey.African health sciences · 2024Article
- Thermoregulation for very preterm infants in the delivery room: a narrative review.Pediatric research · 2024Review
- Quality improvement in the golden hour for premature infants: a scoping review.BMC pediatrics · 2024Article
- Preclinical validation of NeoWarm, a low-cost infant warmer and carrier device, to ameliorate induced hypothermia in newborn piglets as models for human neonates.Frontiers in pediatrics · 2024Article
- Early Neuroprotective Effects of Bovine Lactoferrin Associated with Hypothermia after Neonatal Brain Hypoxia-Ischemia in Rats.International journal of molecular sciences · 2023Article
- Preterm Birth: Screening and Prediction.International journal of women's health · 2023Review
- Admission temperature and neonatal outcomes - single-centre experience in Saudi Arabia.International journal of pediatrics & adolescent medicine · 2022Article
- The effect of maternal anaemia on low birth weight among newborns in Northwest Ethiopia.Scientific reports · 2022Article
- Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study.Children (Basel, Switzerland) · 2022Article
- Reducing intraventricular hemorrhage following the implementation of a prevention bundle for neonatal hypothermia.PloS one · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeonatal hypothermia remains a common problem and is related to elevated morbidities and mortality. However, the long-term neurodevelopmental effects of admission hypothermia are still unknown. This study attempted to determine the short-term and long-term consequences of admission hypothermia in VLBW preterm infants. STUDY
designThis retrospective study measured the incidence and compared the outcomes of admission hypothermia in very low birth weight (VLBW) preterm infants in a tertiary-level neonatal intensive care unit. Infants were divided into the following groups: normothermia (36.5-37.5°C), mild hypothermia (36.0-36.4°C), moderate hypothermia (32.0-35.9°C), and severe hypothermia (< 32°C). We compared the distribution, demographic variables, short-term outcomes, and neurodevelopmental outcomes at 24 months of corrected age among groups.
resultsWe studied 341 infants: 79 with normothermia, 100 with mild hypothermia, 162 with moderate hypothermia, and 0 with severe hypothermia. Patients in the moderate hypothermia group had significantly lower gestational ages (28.1 wk vs. 29.7 wk, P < .02) and smaller birth weight (1004 g vs. 1187 g, P < .001) compared to patients in the normothermia group. Compared to normothermic infants, moderately hypothermic infants had significantly higher incidences of 1-min Apgar score < 7 (63.6% vs. 31.6%, P < .001), respiratory distress syndrome (RDS) (58.0% vs. 39.2%, P = .006), and mortality (18.5% vs. 5.1%, P = .005). Moderate hypothermia did not affect neurodevelopmental outcomes at 2 years' corrected age. Mild hypothermia had no effect on short-term or long-term outcomes.
conclusionsAdmission hypothermia was common in VLBW infants and correlated inversely with birth weight and gestational age. Although moderate hypothermia was associated with higher RDS and mortality rates, it may play a limited role among multifactorial causes of neurodevelopmental impairment.
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