Evidence map›Paper›PMID 26193340›Full record

SynthesisScientific reports2015

Relationship between Diabetic Retinopathy and Subclinical Hypothyroidism: a meta-analysis.

Jingyang Wu, Song Yue, Jin Geng, Limin Liu, Weiping Teng, Lei Liu, Lei Chen

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  18. Thyroid Dysfunction and Type 2 Diabetes Mellitus: Screening Strategies and Implications for Management.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jingyang WuDepartment of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Song YueDepartment of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Jin GengDepartment of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Limin LiuDepartment of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Weiping TengDepartment of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Lei Liu1] Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China [2] Department of Epidemiology. School of Public Health, China Medical University, Shenyang 110001, People's Republic of China.
Lei Chen1] Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China [2] Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
China Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several epidemiological studies have found a positive association between diabetic retinopathy (DR) and subclinical hypothyroidism (SCH), but the findings are varied or even contradictory. In the work, we performed a meta-analysis to ascertain the relationship between DR and SCH. We searched relevant studies on the relationship between DR and SCH. All English reports were used Medline, EMbase, Web of Science, Google scholar, and all Chinese ones used CBMDisc (Chinese Biochemical Literature on Disc) and CNKI (China National Knowledge Infrastructure) database. Meta-analysis was performed using RevMan 5.1 software. We obtained eight observational studies. Random-effects meta-analysis indicated a significant association between DR and SCH (odds ratio = 2.13, 95% confidence interval = 1.41 - 3.23, p < 0.001). Based on currently evidence, SCH is probably a significant risk factor for DR.

Indexed as

Case-Control StudiesDiabetic RetinopathyHumansHypothyroidismRisk Factors

Identifiers

PMID26193340
PMCPMC4507396
OpenAlexW2253086230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.