Evidence map›Paper›PMID 26193289›Full record

ReviewInternational journal of environmental research and public health2015

PM2.5 and Cardiovascular Diseases in the Elderly: An Overview.

Chenchen Wang, Yifan Tu, Zongliang Yu, Rongzhu Lu

Abstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Trial
  2. Article
  3. Quantifying the Health Benefits Linked to Reduced Traffic-Related PMEnvironment & health (Washington, D.C.) · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. PMEco-Environment & Health · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Long-term exposure to PMEnvironmental research · 2025
    Article
  12. SIRT1-Mediated Epigenetic Protective Mechanisms of Phytosome-EncapsulatedInternational journal of molecular sciences · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenchen WangDepartment of Clinical Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China. 2434009969@qq.com.
Yifan TuDepartment of Clinical Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China. 501875090@qq.com.
Zongliang YuDepartment of Cardiology, The First People's Hospital of Kunshan Affiliated to Jiangsu University, 91 Qianjin West Road, Kunshan 215132, China. zongliang-yu@163.com.
Rongzhu LuDepartment of Preventive Medicine and Public Health Laboratory Sciences, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China. lurz@mail.ujs.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the leading cause of mortality and morbidity in the elderly and the ambient concentration of PM2.5 has been associated with several cardiovascular diseases.

methodsWe describe the present state of planetary air pollution, analyze epidemiological studies linking PM2.5 and CVD, and discuss multiple pathophysiological mechanisms linking PM2.5 and CVD.

resultsA few epidemiological studies show that the elderly appear specifically susceptible to adverse cardiovascular effects triggered by PM2.5 exposure. Plausible pathophysiological mechanisms include inflammatory dysfunction, oxidative stress, abnormal activation of the hemostatic system and disturbance of the autonomic nervous system.

conclusionsAn in-depth knowledge of the chemical compounds, pathophysiological mechanisms, and epidemiological studies of PM2.5 are recommended to understand this important and modifiable factor contributing to geriatric CVD burden. We offer public health recommendations to reduce this preventable cause of disease and death.

Indexed as

AgedAir PollutantsAir PollutionCardiovascular DiseasesEpidemiologic StudiesHumansOxidative StressParticulate MatterPublic HealthAir PollutantsParticulate MatterCardiovascular disease (CVD)PM2.5susceptibilitythe elderly

Identifiers

PMID26193289
PMCPMC4515716

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.