ArticleClinical journal of gastroenterology2009
A case of anaplastic carcinoma of the pancreas producing granulocyte-colony stimulating factor.
Article in Clinical journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- A case of resected anaplastic carcinoma of the pancreas producing granulocyte-colony stimulating factor with literature review.Surgical case reports · 2024Article
- One size does not fit all for pancreatic cancers: A review on rare histologies and therapeutic approaches.World journal of gastrointestinal oncology · 2020Review
- Successful resection of a granulocyte colony-stimulating factor-producing carcinoma of the pancreas: A case report.Molecular and clinical oncology · 2019Article
- Granulocyte-colony stimulating factor producing mucinous cystic neoplasm with an associated invasive carcinoma of the pancreas.Oncology letters · 2018Article
- Anaplastic carcinoma of the pancreas: Case report and literature review of reported cases in Japan.World journal of gastroenterology · 2016Review
- Aggressive Recurrent Pancreatic Cancer Producing Granulocyte Colony-Stimulating Factor.Case reports in gastroenterologyArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of anaplastic carcinoma of the pancreas with production of granulocyte-colony stimulating factor (G-CSF) in a 59-year-old male. He was referred to our hospital with a chief complaint of epigastralgia and suffered from leukocytosis. Differential diagnosis included pancreatic tumors and submucosal tumor of the stomach, but definite preoperative diagnosis could not be made. He underwent distal pancreactomy, total gastrectomy with Roux-en-Y reconstruction and splenectomy. He recovered uneventfully postoperatively and was discharged from hospital on the 14th postoperative day. Histological examination showed anaplastic carcinoma of the pancreas. Since the peripheral leukocyte count was sharply decreased after the operation, we suspected the tumor would be producing G-CSF. Then immunohistochemistry showed a positive stain in the tumor. Therefore, we diagnosed the tumor as anaplastic carcinoma of the pancreas producing G-CSF. Three months after the resection, local recurrence was detected by abdominal computed tomography. The patient died of hemorrhagic shock due to tumor invasion of the intestine 8 months after the operation.
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