ArticleNeuroscience and biobehavioral reviews2015
Commentary on "Autism, oxytocin and interoception": Alexithymia, not Autism Spectrum Disorders, is the consequence of interoceptive failure.
Article in Neuroscience and biobehavioral reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Alexithymia in neurodevelopmental populations: a scoping review of Down syndrome, autism spectrum disorder, and dual diagnosis.Frontiers in psychology · 2026Pooled it
- Pooled it
- Investigating alexithymia in autism: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2019Pooled it
- Trial
- Functional neuroanatomy of interoceptive processing in children and adolescents: a pilot study.Scientific reports · 2019Trial
- Oxytocin Modulates Attention Switching Between Interoceptive Signals and External Social Cues.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- A Reliable Effect of Alexithymia, but Not Autism, on Placebo Hypoalgesia.Autism : the international journal of research and practice · 2026Article
- The Relationship Between Interoception, Alexithymia, Autistic Traits and Eating Pathology in Autistic Adults.Journal of autism and developmental disorders · 2026Article
- Associations Between Autism and Self-Reported Dimensions of Interoception.Autism : the international journal of research and practice · 2026Article
- From Disruption to Connection: A Family-Based Practice Model for Enhancing Relationships in Families of Autistic Adolescents.Child psychiatry and human development · 2026Article
- Autistic Adult Online Interoception Feasibility Pilot Program.Occupational therapy international · 2026Article
- Restless Legs Syndrome and Impulsive Decision-Making: Impact of Symptom Severity, Chronotype and Interoception.Movement disorders clinical practice · 2025Article
- The meaning of autistic movements.Autism : the international journal of research and practice · 2024Article
- Alexithymia as a Risk Factor for an Internet Addiction in Adolescents and Young Adults with Autism Spectrum Disorder.European journal of investigation in health, psychology and education · 2024Article
- Emoji Identification and Emoji Effects on Sentence Emotionality in ASD-Diagnosed Adults and Neurotypical Controls.Journal of autism and developmental disorders · 2023Article
- Relationships between alexithymia, interoception, and emotional empathy in autism spectrum disorder.Autism : the international journal of research and practice · 2023Article
- The role of interoception in the overlap between eating disorders and autism: Methodological considerations.European eating disorders review : the journal of the Eating Disorders Association · 2022Article
- A network analysis of interoception, self-awareness, empathy, alexithymia, and autistic traits.European archives of psychiatry and clinical neuroscience · 2022Article
- Action Understanding Promoted by Interoception in Children: A Developmental Model.Frontiers in psychology · 2022Review
- Going beyond the DSM in predicting, diagnosing, and treating autism spectrum disorder with covarying alexithymia and OCD: A structural equation model and process-based predictive coding account.Frontiers in psychology · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In "Autism, oxytocin and interoception" (Neuroscience and Biobehavioral Reviews 47, 410-430) Quattrocki and Friston present their theory of the role of oxytocin in interoception from multiple perspectives. The arguments contained therein are compelling, and highlight the fact that interoception, and the role of oxytocin in interoception, should receive more research attention. However, in addition to outlining the role of oxytocin in interoception the authors also suggest that Autism Spectrum Disorder (ASD) is a result of a failure of this system. It is this latter claim that we disagree with, instead suggesting that alexithymia, rather than autism, is most accurately characterised as a general failure of interoception. We review positive evidence that alexithymia produces several of the deficits identified as indicating a failure of interoception, and negative evidence that ASD (in the absence of comorbid alexithymia) is associated with these deficits. We highlight implications for the model, for oxytocin research, and for the clinical management of psychiatric conditions more generally.
Indexed as
Identifiers
26192103What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.