Evidence map›Paper›PMID 26191966›Full record

Trial reportAlzheimer disease and associated disorders

Correlation Between Caregiver Reports of Physical Function and Performance-based Measures in a Cohort of Older Adults With Alzheimer Disease.

Brittany L Bernard, Lauren E Bracey, Kathleen A Lane, Denisha Y Ferguson, Michael A LaMantia, Sujuan Gao, Douglas K Miller, Christopher M Callahan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brittany L Bernard*Indiana University Center for Aging Research†Regenstrief Institute Inc.Departments of ‡Biostatistics§Medicine, Indiana University School of Medicine, Indianapolis, IN.
Lauren E Bracey
Kathleen A Lane
Denisha Y Ferguson
Michael A LaMantia
Sujuan Gao
Douglas K Miller
Christopher M Callahan

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Alzheimer's Disease Multiple Intervention Trial - ADMITR01AG034946 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI CALLAHAN, CHRISTOPHER M · 2010 to 2014
$2.6M
Delirium Evaluation in the Emergency Department for Seniors (DEEDS)K23AG043498 · NIA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LAMANTIA, MICHAEL ANDREW · 2014 to 2018
$633k
NCATS NIH HHS UL1 TR001108NIA NIH HHS K23 AG043498NIA NIH HHS R01 AG034946
6 · The paper itself

Abstract

The objectives of this report are to determine the association between performance-based measures of physical function with caregiver reports of physical function in older adults with Alzheimer disease (AD) and to examine whether those associations vary by the level of patients' cognitive functioning. Subjects included 180 patient-caregiver dyads who are enrolled in a clinical trial testing the impact of an occupational therapy intervention plus guideline-level care to delay functional decline among older adults with AD. The primary caregiver-reported measure is the Alzheimer's Disease Cooperative Study Group Activities of Daily Living Inventory (ADCS-ADL). Performance-based measures include the Short Physical Performance Battery and the Short Portable Sarcopenia Measure. Analysis of covariance (ANCOVA) models were used to determine the associations of each physical performance measure with ADCS-ADL, adjusting for cognition function and other covariates. We found significant correlations between caregiver reports and observed performance-based measures across all levels of cognitive function, with patients in the lowest cognitive group showing the highest correlation. These findings support the use of proxy reports to assess physical function among older adults with AD.

Indexed as

Activities of Daily LivingAgedAlzheimer DiseaseCaregiversCognitionExercise TestFemaleHumansMaleMiddle AgedNeuropsychological TestsOccupational TherapySingle-Blind Method

Identifiers

PMID26191966
PMCPMC4715794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.