Evidence map›Paper›PMID 26191801›Full record

ArticleClinical journal of gastroenterology2009

Irritable bowel syndrome and inflammatory bowel disease: infectious gastroenteritis-related disorders?

Shunji Ishihara, Monowar Aziz, Naoki Oshima, Yoshiyuki Mishima, Hiroshi Imaoka, Ichiro Moriyama, Yoshikazu Kinoshita

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Dysbiotic infection in the stomach.World journal of gastroenterology · 2015
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shunji IshiharaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan. si360405@med.shimane-u.ac.jp.
Monowar AzizDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Naoki OshimaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Yoshiyuki MishimaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Hiroshi ImaokaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Ichiro MoriyamaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Yoshikazu KinoshitaDepartment of Internal Medicine II, Faculty of Medicine, Shimane University, 89-1, Enya-cho, Izumo, Shimane, Japan.
Shimane University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious gastroenteritis may be one of the important factors in the development of irritable bowel syndrome (IBS), with affected individuals often categorized as having post-infectious IBS (PI-IBS), and is linked to the onset of symptoms in approximately 10-20% of patients diagnosed with IBS. Intestinal mucosal infiltration of T cells and mast cells, and enterochromaffin cell hyperplasia are significant immunological and pathological findings that reveal the pathogenesis of PI-IBS, and results of laboratory studies using animal models of PI-IBS clearly support clinical evidence. Recently, infectious gastroenteritis has also been suggested to be associated with the development of inflammatory bowel disease (IBD), and various studies have suggested that individuals with IBS or IBS-like symptoms may be susceptible to initiation of IBD. However, it is still unclear whether infectious gastroenteritis is directly or indirectly (through PI-IBS) linked to the initiation of IBD. Additional studies are necessary to understand the clinical overlap among infectious gastroenteritis, IBS, and IBD.

Indexed as

GastroenteritisInflammatory bowel disease (IBD)Irritable bowel syndrome (IBS)Post-infectious IBS

Identifiers

PMID26191801
OpenAlexW2030539185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.